Lipidomic landscape in cancer: Actionable insights for membrane‐based therapy and diagnoses
Cancer cells display altered cellular lipid metabolism, including disruption in endogenous
lipid synthesis, storage, and exogenous uptake for membrane biogenesis and functions …
lipid synthesis, storage, and exogenous uptake for membrane biogenesis and functions …
Model architectures for bacterial membranes
The complex composition of bacterial membranes has a significant impact on the
understanding of pathogen function and their development towards antibiotic resistance. In …
understanding of pathogen function and their development towards antibiotic resistance. In …
[HTML][HTML] Mechanopathology of biofilm-like Mycobacterium tuberculosis cords
Mycobacterium tuberculosis (Mtb) cultured axenically without detergent forms biofilm-like
cords, a clinical identifier of virulence. In lung-on-chip (LoC) and mouse models, cords in …
cords, a clinical identifier of virulence. In lung-on-chip (LoC) and mouse models, cords in …
The whole is bigger than the sum of its parts: drug transport in the context of two membranes with active efflux
VV Rybenkov, HI Zgurskaya, C Ganguly… - Chemical …, 2021 - ACS Publications
Cell envelope plays a dual role in the life of bacteria by simultaneously protecting it from a
hostile environment and facilitating access to beneficial molecules. At the heart of this ability …
hostile environment and facilitating access to beneficial molecules. At the heart of this ability …
Transporters involved in the biogenesis and functionalization of the mycobacterial cell envelope
The biology of mycobacteria is dominated by a complex cell envelope of unique composition
and structure and of exceptionally low permeability. This cell envelope is the basis of many …
and structure and of exceptionally low permeability. This cell envelope is the basis of many …
Lipoarabinomannan as a point-of-care assay for diagnosis of tuberculosis: how far are we to use it?
J Flores, JC Cancino, L Chavez-Galan - Frontiers in microbiology, 2021 - frontiersin.org
Tuberculosis (TB) is still a severe public health problem; the current diagnostic tests have
limitations that delay treatment onset. Lipoarabinomannan (LAM) is a glycolipid that is a …
limitations that delay treatment onset. Lipoarabinomannan (LAM) is a glycolipid that is a …
Mycobacterial membranes as actionable targets for lipid-centric therapy in tuberculosis
B Modak, S Girkar, R Narayan… - Journal of Medicinal …, 2022 - ACS Publications
Infectious diseases remain significant health concerns worldwide, and resistance is
particularly common in patients with tuberculosis caused by Mycobacterium tuberculosis …
particularly common in patients with tuberculosis caused by Mycobacterium tuberculosis …
Supramolecular organisation and dynamics of mannosylated phosphatidylinositol lipids in the mycobacterial plasma membrane
661-Pos Supramolecular organisation and dynamics of mannosylated phosphatidylinositol
lipids in the mycobacterial plasma membrane Chelsea M. Brown1, Robin A. Corey2, Ya …
lipids in the mycobacterial plasma membrane Chelsea M. Brown1, Robin A. Corey2, Ya …
Decoding the role of mycobacterial lipid remodelling and membrane dynamics in antibiotic tolerance
Current treatments for tuberculosis primarily target Mycobacterium tuberculosis (Mtb)
infections, often neglecting the emerging issue of latent tuberculosis infection (LTBI) which …
infections, often neglecting the emerging issue of latent tuberculosis infection (LTBI) which …
A critical review of short antimicrobial peptides from scorpion venoms, their physicochemical attributes, and potential for the development of new drugs
PA Fong-Coronado, V Ramirez… - The Journal of …, 2024 - Springer
Scorpion venoms have proven to be excellent sources of antimicrobial agents. However,
although many of them have been functionally characterized, they remain underutilized as …
although many of them have been functionally characterized, they remain underutilized as …