[HTML][HTML] Single-cell transcriptional dynamics in a living vertebrate
The ability to quantify transcriptional dynamics in individual cells via live imaging has
revolutionized our understanding of gene regulation. However, such measurements are …
revolutionized our understanding of gene regulation. However, such measurements are …
Principles of bursty mRNA expression and irreversibility in single cells and extrinsically varying populations
J Holehouse - arXiv preprint arXiv:2405.12897, 2024 - arxiv.org
The canonical model of mRNA expression is the telegraph model, describing a gene that
switches on and off, subject to transcription and decay. It describes steady-state mRNA …
switches on and off, subject to transcription and decay. It describes steady-state mRNA …