Regulation of TNF-induced osteoclast differentiation

Z Yao, SJ Getting, IC Locke - Cells, 2021 - mdpi.com
Increased osteoclast (OC) differentiation and activity is the critical event that results in bone
loss and joint destruction in common pathological bone conditions, such as osteoporosis …

The multifaceted biology of plasmacytoid dendritic cells

M Swiecki, M Colonna - Nature Reviews Immunology, 2015 - nature.com
Plasmacytoid dendritic cells (pDCs) are a unique DC subset that specializes in the
production of type I interferons (IFNs). pDCs promote antiviral immune responses and have …

Universal immunotherapeutic strategy for hepatocellular carcinoma with exosome vaccines that engage adaptive and innate immune responses

B Zuo, Y Zhang, K Zhao, L Wu, H Qi, R Yang… - Journal of hematology & …, 2022 - Springer
Background Personalized immunotherapy utilizing cancer vaccines tailored to the tumors of
individual patients holds promise for tumors with high genetic heterogeneity, potentially …

Dendritic cell subsets and locations

S Balan, M Saxena, N Bhardwaj - International review of cell and molecular …, 2019 - Elsevier
Dendritic cells (DCs) are a unique class of immune cells that act as a bridge between innate
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …

Bovine cryptosporidiosis: impact, host-parasite interaction and control strategies

S Thomson, CA Hamilton, JC Hope, F Katzer… - Veterinary …, 2017 - Springer
Gastrointestinal disease caused by the apicomplexan parasite Cryptosporidium parvum is
one of the most important diseases of young ruminant livestock, particularly neonatal calves …

The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting

M Merad, P Sathe, J Helft, J Miller… - Annual review of …, 2013 - annualreviews.org
Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune
responses according to peripheral cues. After four decades of research, we now know that …

IL-7: comprehensive review

H Winer, GOL Rodrigues, JA Hixon, FB Aiello, TC Hsu… - Cytokine, 2022 - Elsevier
Overview IL-7 is a member of the family of cytokines with four anti-parallel α helixes that bind
Type I cytokine receptors. It is produced by stromal cells and is required for development …

Defining GM-CSF–and macrophage-CSF–dependent macrophage responses by in vitro models

DC Lacey, A Achuthan, AJ Fleetwood… - The Journal of …, 2012 - journals.aai.org
Abstract GM-CSF and M-CSF (CSF-1) induce different phenotypic changes in macrophage
lineage populations. The nature, extent, and generality of these differences were assessed …

Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage

MM Meredith, K Liu, G Darrasse-Jeze… - Journal of Experimental …, 2012 - rupress.org
Classical dendritic cells (cDCs), monocytes, and plasmacytoid DCs (pDCs) arise from a
common bone marrow precursor (macrophage and DC progenitors [MDPs]) and express …

Re (de) fining the dendritic cell lineage

AT Satpathy, X Wu, JC Albring, KM Murphy - Nature immunology, 2012 - nature.com
Dendritic cells (DCs) are essential mediators of innate and adaptive immune responses.
Study of these critical cells has been complicated by their similarity to other hematopoietic …