Fifteen quinazoline derivatives were designed and synthesized as DNA intercalators. The
cytotoxicity of the designed members was assessed against HCT-116 and HepG2 cancer …

Synthesis of some new derivatives of 2‐aryl‐4‐oxo‐1‐(4‐quinazolyl) quinazolines is
described. Methyl N‐(4‐quinazolyl) anthranilate was allowed to react with phenyl iso (thio) …

Introduction: Phosphodiesterase 7 (PDE7) is a high-affinity cyclic AMP (cAMP)-specific PDE
that is expressed in immune and proinflammatory cells. In this work, we explore the …

Abstract A series of 14 new 3‐[4 (3H)‐quinazolinone‐2‐(yl) thiomethyl]‐1, 2, 4‐triazoles
were prepared and characterized by elemental analyses, IR,[1H] NMR and mass spectral …

Quinazolinylaminothiourea 1 selectively recognized AcO−, F− and H2PO4− over other
anions in CH3CN–DMSO (99: 1, v/v), which was accompanied with a visible color change …

Abstract Some [1, 2, 4] triazolo [1, 5‐c] quinazolin‐5 (6H)‐ones 7, the corresponding isomers
[1, 2, 4] triazolo [4, 3‐c] quinazo‐lin‐5 (6H)‐ones and the 5‐amino derivatives 8, 9 and 11 …

An efficient route suitable for a large-scale preparation of KF31327 (1), a potent
phosphodiesterase V inhibitor, has been developed. We selected 7-chloro-2, 4 (1 H, 3 H) …

Fluorine-containing quinazolines annulated at the sides [a] and [c] were synthesized by the
reaction of 2-and 4-hydrazino-substituted quinazolines with aldehydes and subsequent …

A synthetic route for the preparation of 9-phenyl-1, 2, 4-triazolo [4, 3-c] pteridines 8 is
described. Their reactivities towards xanthine oxidase from Arthrobacter M-4 are determined …

The hydrazine derivative 2 has been utilized for the synthesis of three different fused 1, 2, 4-
triazolo [4, 3-a] pyrimidine derivatives 4, 5 & 6 and a tetrazolo [1, 5-a] pyrimidine derivative 7 …