Simple Summary Within this review article the authors provide an unbiased review of the
oncolytic virus, reovirus, clinically formulated as pelareorep. In particular, the authors …

Oncolytic viruses are designed to specifically target cancer cells, sparing normal cells.
Although numerous studies demonstrate the ability of oncolytic viruses to infect a wide range …

Simple Summary Oncolytic viruses (OV) are engineered viruses designed to replicate
selectively within tumour cells. They hold great promise as novel cancer therapeutics, but …

Oncolytic viruses (OVs) are an emerging cancer therapeutic that are intended to act by
selectively targeting and lysing cancerous cells and by stimulating anti-tumour immune …

Viruses have some characteristics in common with cell-based life. They can evolve and
adapt to environmental conditions. Directed evolution can be used by researchers to …

Oncolytic viruses (OVs) are promising alternative biological agents for treating cancer.
However, triggered immune responses against viruses and their delivery to tumor sites are …

At the end of my doctoral studies, in 1988, I published a review article on the major steps of
transcription and translation during the mammalian reovirus multiplication cycle, a topic that …

The role of several risk factors, such as pollution, consumption of alcohol, age, sex and
obesity in cancer progression is undeniable. Human malignancies are mainly characterized …

Cancer is a major health problem. Most of the treatments exhibit systemic toxicity, as they
are not targeted or specific to cancerous cells and tumors. Adenoviruses are very promising …

Breast cancer is the second leading cause of cancer-related deaths in women in the United
States. Triple-negative breast cancer constitutes a subset of breast cancer that is associated …