Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …

Pseudomonas aeruginosa is one of the six bacterial pathogens, Enterococcus faecium,
Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …

Pseudomonas aeruginosa is an opportunistic pathogen affecting immunocompromised
patients. It is known as the leading cause of morbidity and mortality in cystic fibrosis (CF) …

BACKGROUND The escalating crisis of multidrug resistance is raising fears of untreatable
infections caused by bacterial “superbugs.” However, many patients already suffer from …

Surface-associated microbial communities, called biofilms, are present in all environments.
Although biofilms play an important positive role in a variety of ecosystems, they also have …

Persisters are transiently tolerant variants that allow populations to avoid eradication by
antibiotic treatment. Their antibiotic tolerance is non-genetic, not inheritable and results from …

Bacteria encounter a myriad of stresses in their natural environments, including, for
pathogens, their hosts. These stresses elicit a variety of specific and highly regulated …

Lung infection is the main cause of morbidity and mortality in patients with cystic fibrosis and
is mainly dominated by Pseudomonas aeruginosa. The biofilm mode of growth makes …

Certain infectious diseases caused by pathogenic bacteria are typically chronic in nature.
Potentially deadly examples include tuberculosis, caused by Mycobacterium tuberculosis …

We review the recent advances in the understanding of the Pseudomonas aeruginosa
biofilm lifestyle from studies using in vitro laboratory setups such as flow chambers and …