Bone tissue engineering in the treatment of bone defects

N Xue, X Ding, R Huang, R Jiang, H Huang, X Pan… - Pharmaceuticals, 2022 - mdpi.com
Bones play an important role in maintaining exercise and protecting organs. Bone defect, as
a common orthopedic disease in clinics, can cause tremendous damage with long treatment …

[HTML][HTML] Role of FGFR3 in bladder cancer: Treatment landscape and future challenges

CM Ascione, F Napolitano, D Esposito… - Cancer Treatment …, 2023 - Elsevier
Bladder cancer is a heterogeneous malignancy and is responsible for approximately 3.2%
of new diagnoses of cancer per year (Sung et al., 2021). Fibroblast Growth Factor Receptors …

Carboxymethyl chitosan-based hydrogels containing fibroblast growth factors for triggering diabetic wound healing

Y Hao, W Zhao, H Zhang, W Zheng, Q Zhou - Carbohydrate Polymers, 2022 - Elsevier
Triggering the repair process of diabetic wounds is a huge clinical challenge due to
microbial infection, the reduced migration and proliferation of fibroblasts, decreased …

[HTML][HTML] Multi-organ proteomic landscape of COVID-19 autopsies

X Nie, L Qian, R Sun, B Huang, X Dong, Q Xiao… - Cell, 2021 - cell.com
The molecular pathology of multi-organ injuries in COVID-19 patients remains unclear,
preventing effective therapeutics development. Here, we report a proteomic analysis of 144 …

Exercise and nutrition impact on osteoporosis and sarcopenia—the incidence of osteosarcopenia: a narrative review

SK Papadopoulou, K Papadimitriou, G Voulgaridou… - Nutrients, 2021 - mdpi.com
Osteoporosis and sarcopenia are diseases which affect the myoskeletal system and often
occur in older adults. They are characterized by low bone density and loss of muscle mass …

[HTML][HTML] Bioinks and bioprinting technologies to make heterogeneous and biomimetic tissue constructs

N Ashammakhi, S Ahadian, C Xu, H Montazerian… - Materials Today Bio, 2019 - Elsevier
The native tissues are complex structures consisting of different cell types, extracellular
matrix materials, and biomolecules. Traditional tissue engineering strategies have not been …

Skin tissue engineering: wound healing based on stem-cell-based therapeutic strategies

A Nourian Dehkordi, F Mirahmadi Babaheydari… - Stem cell research & …, 2019 - Springer
Normal wound healing is a dynamic and complex multiple phase process involving
coordinated interactions between growth factors, cytokines, chemokines, and various cells …

Mesenchymal stem cell secretome: toward cell-free therapeutic strategies in regenerative medicine

FJ Vizoso, N Eiro, S Cid, J Schneider… - International journal of …, 2017 - mdpi.com
Earlier research primarily attributed the effects of mesenchymal stem cell (MSC) therapies to
their capacity for local engrafting and differentiating into multiple tissue types. However …

Influence of the pore size and porosity of selective laser melted Ti6Al4V ELI porous scaffold on cell proliferation, osteogenesis and bone ingrowth

Z Chen, X Yan, S Yin, L Liu, X Liu, G Zhao, W Ma… - Materials Science and …, 2020 - Elsevier
This paper systematically investigates the biomedical performance of selective laser melted
(SLM) porous Ti6Al4V ELI scaffolds for bone implantation through in vitro and in vivo …

The roles of signaling pathways in bone repair and regeneration

M Majidinia, A Sadeghpour… - Journal of cellular …, 2018 - Wiley Online Library
Regenerative medicine has sparked interest in potential strategies for bone repair. Bone
defects are widespread and could be caused by trauma, congenital malformations …