Therapeutic promotion of intestinal regeneration holds great promise, but defining the
cellular mechanisms that influence tissue regeneration remains an unmet challenge. To …

Xenobiotic receptors, such as the pregnane X receptor, regulate multiple host physiologic
pathways including xenobiotic metabolism, certain aspects of cellular metabolism, and …

The liver X receptor (LXR) is a key transcriptional regulator of cholesterol, fatty acid, and
phospholipid metabolism. Dynamic remodeling of immunometabolic pathways, including …

Abstract T helper 17 cells (Th17) have been associated with the pathogenesis of
autoimmune and inflammatory diseases, which makes them become a sharp focus when the …

Purpose: To investigate the effects and mechanisms of fenofibrate, a synthetic ligand of
peroxisome proliferator-activated receptor α (PPAR-α), on autoimmune dacryoadenitis in a …

The initiation and progression of autoimmune disorders such as multiple sclerosis (MS) is
linked to aberrant cholesterol metabolism and overt inflammation. Liver X receptors (LXR) …

Liver transplantation (LT) stands as the gold standard for treating end‐stage liver disease
and hepatocellular carcinoma, yet postoperative complications continue to impact survival …

The brain is the most lipid-rich organ of the human body. Emerging evidence indicates that
perturbed cholesterol and fatty acid metabolism plays a prominent role in the …

Cholesterol is present in almost all eukaryotic cells and has many functions in health and
disease. One of the cell types influenced by cholesterol are T cells. The aim of this review is …

[ES] Los macrófagos pueblan todos los tejidos del organismo y son imprescindibles para su
homeostasis. Los macrófagos muestran un espectro de fenotipos o estados de polarización …