Omicron variant of SARS‐CoV‐2: genomics, transmissibility, and responses to current COVID‐19 vaccines

Y Araf, F Akter, Y Tang, R Fatemi… - Journal of medical …, 2022 - Wiley Online Library
Currently, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has spread
worldwide as an Omicron variant. This variant is a heavily mutated virus and designated as …

Lessons learned 1 year after SARS-CoV-2 emergence leading to COVID-19 pandemic

KKW To, S Sridhar, KHY Chiu, DLL Hung… - Emerging microbes & …, 2021 - Taylor & Francis
Without modern medical management and vaccines, the severity of the Coronavirus
Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome (SARS) …

Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study

KM Hastie, H Li, D Bedinger, SL Schendel… - Science, 2021 - science.org
Antibody-based therapeutics and vaccines are essential to combat COVID-19 morbidity and
mortality after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

[HTML][HTML] Sensitivity of infectious SARS-CoV-2 B. 1.1. 7 and B. 1.351 variants to neutralizing antibodies

D Planas, T Bruel, L Grzelak, F Guivel-Benhassine… - Nature medicine, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B. 1.1. 7 and B. 1.351
variants were first identified in the United Kingdom and South Africa, respectively, and have …

Estimated transmissibility and impact of SARS-CoV-2 lineage B. 1.1. 7 in England

NG Davies, S Abbott, RC Barnard, CI Jarvis… - Science, 2021 - science.org
INTRODUCTION Several novel variants of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), the virus that causes COVID-19, emerged in late 2020. One of these, Variant …

[HTML][HTML] Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020

K Leung, MHH Shum, GM Leung, TTY Lam… - …, 2021 - eurosurveillance.org
Two new SARS-CoV-2 lineages with the N501Y mutation in the receptor-binding domain of
the spike protein spread rapidly in the United Kingdom. We estimated that the earlier 501Y …

[HTML][HTML] Reduced neutralization of SARS-CoV-2 B. 1.1. 7 variant by convalescent and vaccine sera

P Supasa, D Zhou, W Dejnirattisai, C Liu, AJ Mentzer… - Cell, 2021 - cell.com
SARS-CoV-2 has caused over 2 million deaths in little over a year. Vaccines are being
deployed at scale, aiming to generate responses against the virus spike. The scale of the …

[HTML][HTML] Omicron: a heavily mutated SARS-CoV-2 variant exhibits stronger binding to ACE2 and potently escapes approved COVID-19 therapeutic antibodies

M Shah, HG Woo - Frontiers in immunology, 2022 - frontiersin.org
The new SARS-CoV-2 variant of concern “Omicron” was recently spotted in South Africa and
spread quickly around the world due to its enhanced transmissibility. The variant became …

[HTML][HTML] Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B. 1.1. 7

B Meng, SA Kemp, G Papa, R Datir, IATM Ferreira… - Cell reports, 2021 - cell.com
We report severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ΔH69/V70
in multiple independent lineages, often occurring after acquisition of receptor binding motif …

Estimated transmissibility and severity of novel SARS-CoV-2 Variant of Concern 202012/01 in England

NG Davies, S Abbott, RC Barnard, CI Jarvis… - MedRxiv, 2020 - medrxiv.org
A novel SARS-CoV-2 variant, VOC 202012/01, emerged in southeast England in November
2020 and is rapidly spreading towards fixation. Using a variety of statistical and dynamic …