Lactose is one of the most widespread excipients used in the pharmaceutical industry.
Because of its water solubility and acceptable flowability, lactose is generally added into …

This study aimed to illustrate the use of D-optimal mixture design (DOMD) for optimization of
an enhancer containing Dapsone niosomal formula for acne topical treatment. Mixture …

Background The research was aimed with an approach to formulate biphasic extended-
release system of trospium chloride resulting in controlled release of drug up to 24 h with …

The aim of the study was to develop actarit double-layered osmotic pump tablets to
overcome the weak points of actarit common tablets, such as short half-life and large plasma …

The design and development of drug-releasing textiles require a judicial selection of textile
structure and materials and a thorough understanding of the drug-delivery mechanisms that …

The present study aimed to prepare, optimize, and evaluate Tapentadol hydrochloride
controlled porosity osmotic pump (CPOP) and to achieve the drug release at nearly zero …

The study is based on using SeDeM expert system in developing controlled-release
tramadol HCl osmotic tablets and its in-silico physiologically based pharmacokinetic (PBPK) …

Vinpocetine (VNP) is a nootropic agent used in cerebrovascular disorders and dementia. Its
bioavailability is irregular and irreproducible, due to its low solubility in the intestine and …

A fast-dissolving dosage form is an approach used to improve therapeutic efficacy and
bioavailability by avoiding the first-pass metabolism of the cargo. Besides, the approach …

The present study aimed to design and evaluate controlled porosity osmotic pump (CPOP)
tablets of enalapril maleate (ENP) being used for the treatment of hypertension. D-optimal …