A common feature of all epileptic syndromes is the repetitive occurrence of pathological
patterns of synchronous neuronal activity, usually combined with increased neuronal …

The accumulation of β-amyloid (Aβ) is one of the hallmarks of Alzheimer disease (AD).
Beyond the inflammatory reactions promoted by Aβ, it has been demonstrated that the …

Heterozygous mutation or deletion of a lissencephaly gene (Lis1) in humans is associated
with a severe disruption of cortical and hippocampal lamination, cognitive deficit, and severe …

Status epilepticus (SE) is associated with complex reorganization of hippocampal circuits
involving a significant loss of specific subtypes of GABAergic interneurons. While adaptive …

Temporal lobe epilepsy remains a common disorder with no cure and inadequate
treatments, potentially because of an incomplete understanding of how seizures start. CA1 …

Precise detection of brain regions harboring heightened electrical activity plays a central
role in the understanding and treatment of diseases such as epilepsy. Superparamagnetic …

Résumé L'expression synaptique de la sous-unité α5 des récepteurs GABAA (α5-RGABAA)
a été montrée dans les interneurones (INs) inhibiteurs de la zone CA1 de l'hippocampe …

Among the most complex neurological disorders, the epilepsies have been traditionally
associated with hyperexcitability resulting from an impaired balance between excitation and …

La détection précise des régions du cerveau abritant une activité électrique accrue joue un
rôle central dans la compréhension et le traitement de maladies telles que l'épilepsie …

La neurobiología ha tenido un gran desarrollo en los últimos años, especialmente por las
investigaciones realizadas con diferentes agentes neurotóxicos y que han permitido …