Regulation of Pichia pastoris promoters and its consequences for protein production

T Vogl, A Glieder - New biotechnology, 2013 - Elsevier
The methylotrophic yeast Pichia pastoris is a widely used host for heterologous protein
production. Along with favorable properties such as growth to high cell density and high …

Molecular genetics of fungal siderophore biosynthesis and uptake: the role of siderophores in iron uptake and storage

H Haas - Applied microbiology and biotechnology, 2003 - Springer
To acquire iron, all species have to overcome the problems of iron insolubility and toxicity. In
response to low iron availability in the environment, most fungi excrete ferric iron-specific …

Iron acquisition and transcriptional regulation

CD Kaplan, J Kaplan - Chemical reviews, 2009 - ACS Publications
Iron is an essential element for all eukaryotes. The facile ability of iron to gain and lose
electrons permits its participation in a wide variety of oxidation-reduction reactions. Further …

Metal-responsive transcription factors that regulate iron, zinc, and copper homeostasis in eukaryotic cells

JC Rutherford, AJ Bird - Eukaryotic cell, 2004 - Am Soc Microbiol
Iron, copper, and zinc are all essential nutrients. The electron transfer properties of iron and
copper are fundamental to processes such as respiration and photosynthesis. Zinc forms the …

SreA‐mediated iron regulation in Aspergillus fumigatus

M Schrettl, HS Kim, M Eisendle, C Kragl… - Molecular …, 2008 - Wiley Online Library
Aspergillus fumigatus, the most common airborne fungal pathogen of humans, employs two
high‐affinity iron uptake systems: iron uptake mediated by the extracellular siderophore …

Interaction of HapX with the CCAAT‐binding complex—a novel mechanism of gene regulation by iron

P Hortschansky, M Eisendle, Q Al‐Abdallah… - The EMBO …, 2007 - embopress.org
Iron homeostasis requires subtle control systems, as iron is both essential and toxic. In
Aspergillus nidulans, iron represses iron acquisition via the GATA factor SreA, and induces …

Iron and siderophores in fungal–host interactions

L Johnson - Mycological research, 2008 - Elsevier
Most fungi and bacteria express specific mechanisms for the acquisition of iron from the
hosts they infect for their own survival. This is primarily because iron plays a key catalytic …

Monothiol CGFS glutaredoxins and BolA-like proteins:[2Fe-2S] binding partners in iron homeostasis

H Li, CE Outten - Biochemistry, 2012 - ACS Publications
Monothiol glutaredoxins (Grxs) with a signature CGFS active site and BolA-like proteins
have recently emerged as novel players in iron homeostasis. Elegant genetic and …

Compartmentalization of iron between mitochondria and the cytosol and its regulation

U Mühlenhoff, B Hoffmann, N Richter… - European journal of cell …, 2015 - Elsevier
Iron is essential for life. Its coordinated distribution between intracellular compartments and
the adaptation of iron uptake to intracellular demands are central for a balanced iron …

Adaptation of Cryptococcus neoformans to mammalian hosts: integrated regulation of metabolism and virulence

J Kronstad, S Saikia, ED Nielson, M Kretschmer… - Eukaryotic …, 2012 - Am Soc Microbiol
The basidiomycete fungus Cryptococcus neoformans infects humans via inhalation of
desiccated yeast cells or spores from the environment. In the absence of effective immune …