Boolean modeling in systems biology: an overview of methodology and applications

RS Wang, A Saadatpour, R Albert - Physical biology, 2012 - iopscience.iop.org
Mathematical modeling of biological processes provides deep insights into complex cellular
systems. While quantitative and continuous models such as differential equations have been …

Scale-free networks in cell biology

R Albert - Journal of cell science, 2005 - journals.biologists.com
A cell's behavior is a consequence of the complex interactions between its numerous
constituents, such as DNA, RNA, proteins and small molecules. Cells use signaling …

Dynamical systems on networks

MA Porter, JP Gleeson - Frontiers in Applied Dynamical Systems: Reviews …, 2016 - Springer
Traditionally, much of the study of networks has focused on structural features. Indeed,
mathematical subjects such as graph theory have a rich history of investigating network …

Logical modeling and dynamical analysis of cellular networks

W Abou-Jaoudé, P Traynard, PT Monteiro… - Frontiers in …, 2016 - frontiersin.org
The logical (or logic) formalism is increasingly used to model regulatory and signaling
networks. Complementing these applications, several groups contributed various methods …

Dynamical analysis of a generic Boolean model for the control of the mammalian cell cycle

A Fauré, A Naldi, C Chaouiya, D Thieffry - Bioinformatics, 2006 - academic.oup.com
Motivation: To understand the behaviour of complex biological regulatory networks, a proper
integration of molecular data into a full-fledge formal dynamical model is ultimately required …

State feedback stabilization for Boolean control networks

R Li, M Yang, T Chu - IEEE Transactions on Automatic Control, 2013 - ieeexplore.ieee.org
State feedback stabilization for Boolean control networks is investigated in this technical
note. Based on the algebraic representation of logical dynamics in terms of the semi-tensor …

Controllability of Boolean control networks via the Perron–Frobenius theory

D Laschov, M Margaliot - Automatica, 2012 - Elsevier
Boolean control networks (BCNs) are recently attracting considerable interest as
computational models for genetic and cellular networks. Addressing control-theoretic …

Network model of survival signaling in large granular lymphocyte leukemia

R Zhang, MV Shah, J Yang… - Proceedings of the …, 2008 - National Acad Sciences
T cell large granular lymphocyte (T-LGL) leukemia features a clonal expansion of antigen-
primed, competent, cytotoxic T lymphocytes (CTL). To systematically understand signaling …

Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction

J Saez‐Rodriguez, LG Alexopoulos… - Molecular systems …, 2009 - embopress.org
Large‐scale protein signalling networks are useful for exploring complex biochemical
pathways but do not reveal how pathways respond to specific stimuli. Such specificity is …

Predicting essential components of signal transduction networks: a dynamic model of guard cell abscisic acid signaling

S Li, SM Assmann, R Albert - PLoS biology, 2006 - journals.plos.org
Plants both lose water and take in carbon dioxide through microscopic stomatal pores, each
of which is regulated by a surrounding pair of guard cells. During drought, the plant hormone …