Abstract A new SARS coronavirus (SARS-CoV-2) belonging to the genus Betacoronavirus
has caused a pandemic known as COVID-19. Among coronaviruses, the main protease (M …

Schiff base-bearing molecules have been reported to exhibit potent biological activities;
Therefore, the synthesis and applications of these molecules are of great importance. In this …

Abstracts This work used quantum chemical method via DFT to calculate molecular
descriptors for the development of QSAR model to predict bioactivity (IC 50-50% inhibition …

Immunoglobulin A (IgA) nephropathy also known as Berger's disease, is a silent monster
and perhaps the most prevalent glomerulonephritis that often accounts for end-stage kidney …

Accumulation of urate crystals and subsequent inflammation are the major cause of
pathogenesis of gout. Two pro inflammatory cytokines IL17A and IL18 are upregulated in the …

Multidrug resistance is a significant drawback in malaria treatment, and mutations in the
active sites of the many critical antimalarial drug targets have remained challenging …

The advent of antibiotic resistance and the growth of new strains of bacteria are of great
concern to the world health sectors. Effective treatment of the infections caused by these …

Introduction: Drug development in many countriesbegins with medicinal plants usage as
valuable materials. Euphorbia hirta (EH) and Nauclea latifolia (NL) are important medicinal …

Medicinal plants have traditionally provided a source of hope for novel drug compounds with
effectiveness to combat antimicrobial resistance, as plant herbal mixtures have made large …

Abstract The 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole (2HMN) is a powerful
antibacterial and antiparasitic drug used alongside other drugs against Helicobacter pylori …