Genetic, neuropathological and biochemical investigations have revealed meaningful
relationships between aluminum (Al) exposure and neurotoxic and hematotoxic damage …

Sigma-1 receptor agonists have recently gained a great deal of interest due to their anti-
amnesic, neuroprotective, and neurorestorative properties. Compounds such as PRE-084 or …

Biomaterials provide novel platforms to deliver stem cell and growth factor therapies for
central nervous system (CNS) repair. The majority of these approaches have focused on the …

In the core of a brain infarct, loss of neuronal function is followed by neuronal death within
minutes. In an area surrounding the core (penumbra), some perfusion remains. Here …

Epilepsy is a neurological disorder resulting from abnormal neuronal firing in the brain.
Glutamate transporters and the glutamate–glutamine cycle play crucial roles in the …

Epidemiologic studies have indicated that chronic hypertension may facilitate the
progression of abnormal behavior, such as emotional irritability, hyperactivity, and attention …

Genetic, neuropathological and biochemical investigations have revealed meaningful
relationships between aluminum (Al) exposure and neurotoxic and hematotoxic damage …

Background: Glutamate toxicity and reactive oxygen accumulation are life-threatening
factors that play a role in the pathogenesis of neurodegenerative diseases. Today, many …

Glutamate is the major excitatory neurotransmitter in the central nervous system. Excessive
glutamate is known to cause excitotoxicity. Umbelliferone is a coumarin derivative …

Silver nanoparticles (AgNPs) are one of the most highly commercialized nanoparticles,
having been used extensively as an antimicrobial agent in cosmetics, textiles, foods, and the …