We aimed to define the chronically altered gene expression signature of traumatic brain
injury (TBI-sig) to discover novel treatments to reverse pathologic gene expression or …

Transmembrane protein family members (TMEMs) span the entire lipid bilayer and act as
channels that allow the transport of specific substances through biofilms. The functions of …

Prolonged cerebral hypoperfusion after the return of spontaneous circulation (ROSC) from
cardiac arrest (CA) may lead to poor neurological recovery. In a 7-min asphyxia-induced CA …

Traumatic brain injury (TBI) is associated with long-term disabilities and devastating chronic
neurological complications including problems with cognition, motor function, sensory …

We used controlled cortical impact in mice to model human traumatic brain injury (TBI).
Local injury was accompanied by distal diaschisis lesions that developed within brain …

Background Protracted cerebral hypoperfusion following cardiac arrest (CA) may cause
poor neurological recovery. We hypothesized that inhaled carbon dioxide (CO2) could …

Epimedii Herba (EH) has been used in traditional Asian medicine to treat hemiplegia
following stroke. Icariin, its major active component, is used as a quality-control marker and …

Background In most post–cardiac arrest patients, the autoregulation mechanism of cerebral
blood flow (CBF) is dysregulated. We examined whether recovery of CBF by adjusting mean …

Traumatic brain injury (TBI) is a disabling disorder and a major cause of death and disability
in the world. Both single and repetitive traumas affect the brain acutely but can also lead to …

We examined damage and repair processes in the rat cerebellum within the first week
following moderate traumatic brain injury (TBI) induced by lateral fluid percussion injury …