Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies

M Solmi, J Radua, M Olivola, E Croce, L Soardo… - Molecular …, 2022 - nature.com
Promotion of good mental health, prevention, and early intervention before/at the onset of
mental disorders improve outcomes. However, the range and peak ages at onset for mental …

Alzheimer's disease: risk factors and potentially protective measures

MVF Silva, CMG Loures, LCV Alves… - Journal of biomedical …, 2019 - Springer
Alzheimer's disease (AD) is the most common type of dementia and typically manifests
through a progressive loss of episodic memory and cognitive function, subsequently causing …

Cognitive impairment in euthymic major depressive disorder: a meta-analysis

E Bora, BJ Harrison, M Yücel, C Pantelis - Psychological medicine, 2013 - cambridge.org
BackgroundThere is evidence to suggest that cognitive deficits might persist beyond the
acute stages of illness in major depressive disorder (MDD). However, the findings are …

Dementia risk estimates associated with measures of depression: a systematic review and meta-analysis

N Cherbuin, S Kim, KJ Anstey - BMJ open, 2015 - bmjopen.bmj.com
Objectives To perform a systematic review of reported HRs of all cause dementia,
Alzheimer's disease (AD) and vascular dementia (VaD) for late-life depression and …

An insight into cellular and molecular mechanisms underlying the pathogenesis of neurodegeneration in Alzheimer's disease

Y Ratan, A Rajput, S Maleysm, A Pareek, V Jain… - Biomedicines, 2023 - mdpi.com
Alzheimer's disease (AD) is the most prominent neurodegenerative disorder in the aging
population. It is characterized by cognitive decline, gradual neurodegeneration, and the …

Is dysregulation of the HPA-axis a core pathophysiology mediating co-morbid depression in neurodegenerative diseases?

X Du, TY Pang - Frontiers in psychiatry, 2015 - frontiersin.org
There is increasing evidence of prodromal manifestation of neuropsychiatric symptoms in a
variety of neurodegenerative diseases such as Parkinson's disease (PD) and Huntington's …

Epidemiology and etiology of Alzheimer's disease: from genetic to non-genetic factors

T Jiang, JT Yu, Y Tian, L Tan - Current Alzheimer Research, 2013 - ingentaconnect.com
At present, the etiology of Alzheimer's disease (AD) is still unclear, but both genetic and non-
genetic factors are thought to take part in the etiopathogenesis of AD. Epidemiologic …

Risk of Dementia in persons who have previously experienced clinically-significant Depression, Anxiety, or PTSD: A Systematic Review and Meta-Analysis

JK Kuring, JL Mathias, L Ward - Journal of affective disorders, 2020 - Elsevier
Background Depression, anxiety and PTSD appear to be linked to dementia, but it is unclear
whether they are risk factors (causal or prodromal) for, comorbid with, or sequelae to …

Depression as a risk factor for Alzheimer's disease: a systematic review of longitudinal meta-analyses

O Sáiz-Vázquez, P Gracia-García… - Journal of clinical …, 2021 - mdpi.com
Alzheimer's disease (AD) is the most frequent cause of dementia, linked to morbidity and
mortality among elderly patients. Recently, several clinical studies suggested that …

Association between stroke and Alzheimer's disease: systematic review and meta-analysis

J Zhou, JT Yu, HF Wang, XF Meng… - Journal of …, 2014 - journals.sagepub.com
Alzheimer's disease (AD) and stroke are common disorders of aging, but the relationship
between these two disorders remains uncertain. Recent evidence recognized that they …