Cell-SELEX for aptamer discovery and its utilization in constructing electrochemical biosensor for rapid and highly sensitive detection of Legionella pneumophila …

A Shaukat, A Chrouda, S Sadaf, F Alhamlan, S Eissa… - Scientific Reports, 2024 - nature.com
This study introduces an innovative electrochemical aptasensor designed for the highly
sensitive and rapid detection of Legionella pneumophila serogroup 1 (L. pneumophila SG1) …

Nitric oxide signaling through three receptors regulates virulence, biofilm formation, and phenotypic heterogeneity of Legionella pneumophila

S Michaelis, T Chen, C Schmid, H Hilbi - Mbio, 2024 - Am Soc Microbiol
The causative agent of Legionnaires' disease, Legionella pneumophila, is an environmental
bacterium, that replicates in macrophages, parasitizes amoeba, and forms biofilms. L …

[HTML][HTML] Ecology of Legionella pneumophila biofilms: The link between transcriptional activity and the biphasic cycle

A Barbosa, NF Azevedo, DM Goeres, L Cerqueira - Biofilm, 2024 - Elsevier
There has been considerable discussion regarding the environmental life cycle of
Legionella pneumophila and its virulence potential in natural and man-made water systems …

Legionella pneumophila IrsA, a novel, iron-regulated exoprotein that facilitates growth in low-iron conditions and modulates biofilm formation

AE Lopez, J Mayoral, H Zheng… - Microbiology …, 2024 - journals.asm.org
To discover new factors that are involved in iron acquisition by Legionella pneumophila, we
used RNA-Seq to identify the genes that are most highly induced when virulent strain 130b …

Functional Analysis of the $\textit {Legionella pneumophila} $ Nitric Oxide Regulatory Network and its Link to Quorum Sensing

S Michaelis - 2024 - zora.uzh.ch
Legionella pneumophila is a ubiquitous Gram-negative bacterium and the causative agent
of Legionnaires' disease and Pontiac fever. The facultative intracellular bacterium colonizes …

Transcription Factors DksA and PsrA are synergistic contributors to L. pneumophila virulence in Acathamoeba castellanii protozoa

CI Graham, TL MacMartin, TV Penner, JC Beck… - bioRxiv, 2024 - biorxiv.org
The environmental bacterium Legionella pneumophila is an intracellular parasite of free-
living freshwater protozoa, and an opportunistic human pathogen. The L. pneumophila …