In mammals, miRNAs recognize target mRNAs via base pairing, which leads to a complex
'multiple-to-multiple'regulatory network. Previous studies have focused on the regulatory …

The proper formation and function of neuronal networks is required for cognition and
behavior. Indeed, pathophysiological states that disrupt neuronal networks can lead to …

MicroRNA (miRNA or miR) therapeutics in cancer are based on targeting or mimicking
miRNAs involved in cancer onset, progression, angiogenesis, epithelial-mesenchymal …

Since their discovery and the advent of RNA interference, microRNAs have drawn enormous
attention because of their ubiquitous involvement in cellular pathways from life to death, from …

MicroRNAs (miRNAs) are sequentially processed by two RNase III enzymes, Drosha and
Dicer. miR-451 is the only known miRNA whose processing bypasses Dicer and instead …

Anaplastic lymphoma kinase (Alk) and leucocyte tyrosine kinase (Ltk) were identified as
“orphan” receptor tyrosine kinases (RTKs) with oncogenic potential. Recently ALKAL1 and …

Abnormal expression of microRNA-107 (miR-107) was found in non-small cell lung cancer
(NSCLC). However, little is known about its role and molecular mechanism in NSCLC …

The vascular endothelial growth factor (VEGF) is a homodimeric disulfide bound
glycoprotein that promotes endothelial growth, accompanied by higher vascular …

Vertebrate tissues exhibit mechanical homeostasis, showing stable stiffness and tension
over time and recovery after changes in mechanical stress. However, the regulatory …

MicroRNAs (miRNAs) are a class of short non-coding RNAs that operate as prominent post-
transcriptional regulators of eukaryotic gene expression. miRNAs are abundantly expressed …