Recent trends in biocatalysis

D Yi, T Bayer, CPS Badenhorst, S Wu… - Chemical Society …, 2021 - pubs.rsc.org
Biocatalysis has undergone revolutionary progress in the past century. Benefited by the
integration of multidisciplinary technologies, natural enzymatic reactions are constantly …

[HTML][HTML] Relationships between vitamin D, gut microbiome, and systemic autoimmunity

EA Yamamoto, TN Jørgensen - Frontiers in immunology, 2020 - frontiersin.org
There is increasing recognition of the role the microbiome plays in states of health and
disease. Microbiome studies in systemic autoimmune diseases demonstrate unique …

Carnobacterium maltaromaticum boosts intestinal vitamin D production to suppress colorectal cancer in female mice

Q Li, H Chan, WX Liu, CA Liu, Y Zhou, D Huang… - Cancer Cell, 2023 - cell.com
Carnobacterium maltaromaticum was found to be specifically depleted in female patients
with colorectal cancer (CRC). Administration of C. maltaromaticum reduces intestinal tumor …

Vitamin D in inflammatory bowel diseases. Mechanisms of action and therapeutic implications

F Vernia, M Valvano, S Longo, N Cesaro, A Viscido… - Nutrients, 2022 - mdpi.com
(1) Background: Vitamin D is an immunoregulatory factor influencing intestinal homeostasis.
Recent evidence supports a central role of this micronutrient in the course of Inflammatory …

Enzymatic Hydroxylations of sp3-Carbons

J Munch, P Pullmann, W Zhang, MJ Weissenborn - Acs Catalysis, 2021 - ACS Publications
Enzymatic hydroxylation of activated and nonactivated sp3-carbons attracts keen interest
from the chemistry community as it is one of the most challenging tasks in organic synthesis …

Targeting sex steroid biosynthesis for breast and prostate cancer therapy

M Poutanen, M Hagberg Thulin, P Härkönen - Nature Reviews Cancer, 2023 - nature.com
Sex steroids are major promoters of the growth of breast and prostate cancers. This Review
by Poutanen et al. describes the development of treatments for these cancer types that act to …

Immunomodulatory actions of vitamin D in various immune-related disorders: a comprehensive review

A Ghaseminejad-Raeini, A Ghaderi, A Sharafi… - Frontiers in …, 2023 - frontiersin.org
For many years, vitamin D has been acknowledged for its role in maintaining calcium and
phosphate balance. However, in recent years, research has assessed its …

Gut microbiome reveals specific dysbiosis in primary osteoporosis

Z Xu, Z Xie, J Sun, S Huang, Y Chen, C Li… - Frontiers in cellular …, 2020 - frontiersin.org
Object: Primary osteoporosis (PO) is the most common bone disease, which is characterized
by decreased bone mass, damage of bone tissue microstructure, increased bone fragility …

Chemoenzymatic synthesis of C14-functionalized steroids

F Song, M Zheng, J Wang, H Liu, Z Lin, B Liu… - Nature …, 2023 - nature.com
C14-functionalized steroids display biological activity and have been used as medicines.
The lack of synthetic methods to access C14-functionalized steroids has, however, impeded …

Mechanism of β-cypermethrin metabolism by Bacillus cereus GW-01

J Zhao, Y Jiang, L Gong, X Chen, Q Xie, Y Jin… - Chemical Engineering …, 2022 - Elsevier
Pesticide residues in soil and food are of concern for human health. Biodegradation is an
attractive option for reducing these residues, but more insight into the mechanism of …