[HTML][HTML] Mechanisms of tigecycline resistance in Gram-negative bacteria: A narrative review

W Su, W Wang, L Li, M Zhang, H Xu, C Fu… - Engineering …, 2024 - Elsevier
Tigecycline serves as a critical “final-resort” antibiotic for treating bacterial infections caused
by multidrug-resistant bacteria for which treatment options are severely limited. The …

Predicting tigecycline susceptibility in multidrug-resistant Klebsiella species and Escherichia coli strains of environmental origin

JPR Furlan, EG Stehling - Brazilian Journal of Microbiology, 2023 - Springer
Tigecycline (TGC) is an important antimicrobial agent used as a last resort for difficult-to-treat
infections mainly caused by carbapenem-resistant Enterobacteriaceae, but TGC-resistant …

Whole-genome sequence analysis of clinically isolated carbapenem resistant Escherichia coli from Iran

M Haeili, S Barmudeh, M Omrani, N Zeinalzadeh… - BMC microbiology, 2023 - Springer
Background The emergence of carbapenem-resistant Enterobacterales (CRE) continues to
threaten public health due to limited therapeutic options. In the current study the incidence of …

Tetracycline and chloramphenicol exposure induce decreased susceptibility to tigecycline and genetic alterations in AcrAB-TolC efflux pump regulators in Escherichia …

NA Nasralddin, M Haeili, S Karimzadeh, F Alsahlani - PloS one, 2025 - journals.plos.org
Tigecycline (Tgc), a third-generation tetracycline is found as the last line of defense against
multi-drug resistant bacteria. Recent increased rate of resistance to tgc, a human-restricted …

Comparative De Novo and Pan-Genome Analysis of MDR Nosocomial Bacteria Isolated from Hospitals in Jeddah, Saudi Arabia

M Alghamdi, E Al-Judaibi, M Al-Rashede, A Al-Judaibi - Microorganisms, 2023 - mdpi.com
Multidrug-resistant (MDR) bacteria are one of the most serious threats to public health, and
one of the most important types of MDR bacteria are those that are acquired in a hospital …

Development mechanism of resistant population post-exposure to tigecycline in tigecycline-heteroresistant Acinetobacter baumannii strain

J Jo, W Park, DH Kweon, KS Ko - International Journal of Antimicrobial …, 2023 - Elsevier
Tigecycline heteroresistance is highly prevalent in Acinetobacter baumannii clinical isolates,
reducing the efficacy of tigecycline treatment. This study investigated the population …