Obesity is at epidemic proportions in the United States and in other developed and
developing countries. The prevalence of obesity is increasing not only in adults, but …

Overnutrition and sedentary lifestyle result in overweight or obesity defined as abnormal or
excessive fat accumulation that may impair health. According to the WHO, the worldwide …

Obesity-related osteoarthritis (OA) is a complex, multifactorial condition that can cause
significant impact on patients' quality of life. Whilst chronic inflammation, adipocytokines and …

Objective: To determine in a prospective population-based cohort study relationships
between different measures of body mass and the incidence of severe knee and hip …

OBJECTIVE: To explore the relationships between C-reactive protein (CRP), metabolic
syndrome (MetS) and incidence of severe knee or hip osteoarthritis (OA) in a prospective …

Introduction The authors examined how body mass index (BMI) across life is linked to the
risk of midlife knee osteoarthritis (OA), testing whether prolonged exposure to high BMI or …

Introduction Adiponectin has been implicated in the pathogenesis of osteoarthritis (OA). We
studied the effects of adiponectin on the OA cartilage homeostasis. Methods …

Background Research involving more representative samples is needed to extend our
understanding of the broader impact of obesity in hip or knee joint disease (arthritis and OA) …

Osteoarthritis (OA) is a multifactorial disease. Different risk factors have been identified such
as aging and obesity and different models have been used to study the impact of obesity …

Osteoarthritis (OA), the most common form of arthritis, is associated with joint malfunction
and chronic disability in the aged population. It is a multifactorial disorder to which several …