[HTML][HTML] A novel sulfonamide resistance mechanism by two-component flavin-dependent monooxygenase system in sulfonamide-degrading actinobacteria

DW Kim, CN Thawng, K Lee, EMH Wellington… - Environment …, 2019 - Elsevier
Sulfonamide-degrading bacteria have been discovered in various environments, suggesting
the presence of novel resistance mechanisms via drug inactivation. In this study …

Molecular characterization and comparative genomics of IncQ-3 plasmids conferring resistance to various antibiotics isolated from a wastewater treatment plant in …

M Piotrowska, L Dziewit, R Ostrowski, C Chmielowska… - Antibiotics, 2020 - mdpi.com
As small, mobilizable replicons with a broad host range, IncQ plasmids are widely
distributed among clinical and environmental bacteria. They carry antibiotic resistance …

Polymorphism of antibiotic-inactivating enzyme driven by ecology expands the environmental resistome

DW Kim, CN Thawng, JH Choi, K Lee… - The ISME …, 2018 - academic.oup.com
The environmental resistome has been recognized as the origin and reservoir of antibiotic
resistance genes and considered to be dynamic and ever expanding. In this study, a …

Colistin-degrading proteases confer collective resistance to microbial communities during polymicrobial infections

DH Lee, JH Cha, DW Kim, K Lee, YS Kim, HY Oh… - Microbiome, 2022 - Springer
Background The increasing prevalence of resistance against the last-resort antibiotic colistin
is a significant threat to global public health. Here, we discovered a novel colistin resistance …

Functional Identification and Evolutionary Analysis of Two Novel Plasmids Mediating Quinolone Resistance in Proteus vulgaris

H Zhang, M Chang, X Zhang, P Cai, Y Dai, T Song… - Microorganisms, 2020 - mdpi.com
Plasmid-mediated quinolone resistance (PMQR) remains one of the main mechanisms of
bacterial quinolone resistance and plays an important role in the transmission of antibiotic …