Immunosuppressive/anti-inflammatory cytokines directly and indirectly inhibit endothelial dysfunction-a novel mechanism for maintaining vascular function

Y Shao, Z Cheng, X Li, V Chernaya, H Wang… - Journal of hematology & …, 2014 - Springer
Endothelial dysfunction is a pathological status of the vascular system, which can be broadly
defined as an imbalance between endothelium-dependent vasoconstriction and …

Mitochondrial reactive oxygen species mediate lysophosphatidylcholine-induced endothelial cell activation

X Li, P Fang, Y Li, YM Kuo, AJ Andrews… - … , and vascular biology, 2016 - Am Heart Assoc
Objective—Hyperlipidemia-induced endothelial cell (EC) activation is considered as an
initial event responsible for monocyte recruitment in atherogenesis. However, it remains …

IL-35 is a novel responsive anti-inflammatory cytokine—a new system of categorizing anti-inflammatory cytokines

X Li, J Mai, A Virtue, Y Yin, R Gong, X Sha… - PloS one, 2012 - journals.plos.org
It remains unknown whether newly identified anti-inflammatory/immunosuppressive cytokine
interleukin-35 (IL-35) is different from other anti-inflammatory cytokines such as IL-10 and …

[HTML][HTML] Regulation of gene expression by exercise-related micrornas

LN Masi, TDA Serdan, AC Levada-Pires… - Cellular Physiology and …, 2016 - karger.com
Gene expression control by microRNAs (miRs) is an important mechanism for maintenance
of cellular homeostasis in physiological and pathological conditions as well as in response …

MicroRNA-155 deficiency leads to decreased atherosclerosis, increased white adipose tissue obesity, and non-alcoholic fatty liver disease: a novel mouse model of …

A Virtue, C Johnson, J Lopez-Pastraña, Y Shao… - Journal of Biological …, 2017 - ASBMB
Obesity paradox (OP) describes a widely observed clinical finding of improved
cardiovascular fitness and survival in some overweight or obese patients. The molecular …

[HTML][HTML] MicroRNA-155 promotes atherosclerosis inflammation via targeting SOCS1

Y Yang, L Yang, X Liang, G Zhu - Cellular Physiology and Biochemistry, 2015 - karger.com
Aims: Accumulating evidence suggests that atherosclerotic progression depends on
persistent and chronic inflammation in the arterial walls. MicroRNA-155 is reportedly …

Circulating miR-155 and JAK2/STAT3 axis in acute ischemic stroke patients and its relation to post-ischemic inflammation and associated ischemic stroke risk factors

N Adly Sadik, L Ahmed Rashed… - … journal of general …, 2021 - Taylor & Francis
Background “Micro RNAs and their target genes recently have been identified to play a
crucial role in the molecular pathogenesis of post-stroke ischemic cellular injury, which …

Increased expression of resistin in microRNA-155-deficient white adipose tissues may be a possible driver of metabolically healthy obesity transition to classical …

C Johnson, C Drummer IV, A Virtue, T Gao… - Frontiers in …, 2018 - frontiersin.org
We reported that microRNA-155 (miR-155) deficiency in ApoE-/-mice yields a novel
metabolically healthy obese (MHO) model, which exhibits improved atherosclerosis but …

Induction of MiR133a expression by IL-19 targets LDLRAP1 and reduces oxLDL uptake in VSMC

K Gabunia, AB Herman, M Ray, SE Kelemen… - Journal of molecular and …, 2017 - Elsevier
The transformation of vascular smooth muscle cells [VSMC] into foam cells leading to
increased plaque size and decreased stability is a key, yet understudied step in …

Upregulation of miR-142-5p in atherosclerotic plaques and regulation of oxidized low-density lipoprotein-induced apoptosis in macrophages

R Xu, C Bi, J Song, L Wang, C Ge… - Molecular …, 2015 - spandidos-publications.com
Abstract MicroRNA (miR)‑142‑5p is a member of the miR‑142 family, which have been
shown to be associated with tumors, stem cells and disorders of the immune system …