Crosstalk of inflammatory cytokines within the breast tumor microenvironment

O Habanjar, R Bingula, C Decombat… - International journal of …, 2023 - mdpi.com
Several immune and immunocompetent cells, including dendritic cells, macrophages,
adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the …

Estrogen receptor signaling mechanisms

N Fuentes, P Silveyra - Advances in protein chemistry and structural …, 2019 - Elsevier
The primary female sex hormones, estrogens, are responsible for the control of functions of
the female reproductive system, as well as the development of secondary sexual …

Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention

M Picon‐Ruiz, C Morata‐Tarifa… - CA: a cancer journal …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE Recent decades have seen an unprecedented rise in
obesity, and the health impact thereof is increasingly evident. In 2014, worldwide, more than …

The protective role of estrogen and estrogen receptors in cardiovascular disease and the controversial use of estrogen therapy

A Iorga, CM Cunningham, S Moazeni… - Biology of sex …, 2017 - Springer
Epidemiologic studies have previously suggested that premenopausal females have
reduced incidence of cardiovascular disease (CVD) when compared to age-matched males …

The complex role of estrogens in inflammation

RH Straub - Endocrine reviews, 2007 - academic.oup.com
There is still an unresolved paradox with respect to the immunomodulating role of estrogens.
On one side, we recognize inhibition of bone resorption and suppression of inflammation in …

Influence of sex steroid hormones on cerebrovascular function

DN Krause, SP Duckles… - Journal of applied …, 2006 - journals.physiology.org
The cerebral vasculature is a target tissue for sex steroid hormones. Estrogens, androgens,
and progestins all influence the function and pathophysiology of the cerebral circulation …

Obesity and endometrial cancer

E Shaw, M Farris, J McNeil, C Friedenreich - Obesity and cancer, 2016 - Springer
Endometrial cancer is the sixth most common cancer in women worldwide and the most
common gynecologic malignancy in the developed world. This chapter explores the current …

Molecular links between obesity and breast cancer

AM Lorincz, S Sukumar - Endocrine-related cancer, 2006 - erc.bioscientifica.com
Breast cancer continues to be a major health problem for women in the USA and worldwide.
There is a need to identify and take steps to alter modifiable breast cancer risks. Conditions …

Obesity, adipocytokines, and insulin resistance in breast cancer

DP Rose, D Komninou, GD Stephenson - Obesity reviews, 2004 - Wiley Online Library
The adipocytokines are biologically active polypeptides that are produced either exclusively
or substantially by the adipocytes, and act by endocrine, paracrine, and autocrine …

Obesity-related plasma hemodilution and PSA concentration among men with prostate cancer

LL Banez, RJ Hamilton, AW Partin, RT Vollmer, L Sun… - Jama, 2007 - jamanetwork.com
ContextRecent studies have suggested that obese men have lower serum prostate-specific
antigen (PSA) concentrations than nonobese men. Because men with higher body mass …