Histopathological grading of epithelial dysplasia remains the principal laboratory method for
assessing the risk of malignant transformation in oral potentially malignant disorders …

Squamous cell carcinoma arising from oral mucosal epithelium remains a lethal and
deforming disease due to tumour invasion, oro‐facial destruction, cervical lymph node …

Oral leukoplakia (OL) is a potentially malignant oral disorder. The Gold Standard treatment
is to remove surgically the OL. Despite optimal surgery, the recurrence rates are estimated to …

Oral potentially malignant disorders (PMD) are recognisable mucosal conditions that have
an unpredictable risk of transformation to squamous cell carcinoma (SCC), a lethal and …

Objectives The aim of this systematic review was to examine the evidence of the binary
histologic grading system capacity for predicting malignant transformation and to compare it …

Oral squamous cell carcinoma (OSCC) is a lethal disease, with rising incidence. There were
6767 new OSCC cases and 2056 deaths in the UK in 2011. Cancers are preceded by oral …

Background Oral potentially malignant disorders harbour variable and unpredictable risk for
squamous carcinoma development. Whilst current management strategies utilise …

Purpose Oral potentially malignant disorders (OPMDs) may have varying degrees of oral
epithelial dysplasia (OED). Traditional grading schemes separate OED into three-tiers (mild …

Introduction Clinical management of oral potentially malignant disorders relies on accurate
histopathological assessment of the presence and grade of oral epithelial dysplasia. While …

Background Oral potentially malignant disorders (PMD) harbour unpredictable risk for
squamous cell carcinoma development. Current management requires tissue biopsy for …