Oncotherapeutic strategies in early onset colorectal cancer

M O'Reilly, A Linehan, A Krstic, W Kolch, K Sheahan… - Cancers, 2023 - mdpi.com
Simple Summary Early onset colorectal cancer (defined as colorectal cancer in those less
than 50 years of age) is increasing in incidence worldwide. There are many risk factors for …

Colorectal cancer in the young: research in early age colorectal cancer trends (REACCT) collaborative

AM Zaborowski - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer is becoming more common in adults under 50. This
trend has been observed worldwide, the reasons for which are unclear. Research has …

A decade-long study on pathological distinctions of resectable early versus late onset colorectal cancer and optimal screening age determination

J Song, T Han, L Qian, J Zhu, Y Qiao, S Liu, P Yu… - Scientific Reports, 2024 - nature.com
Abstract The incidence of Early-Onset Colorectal Cancer (EOCRC) is increasing. However,
the prognosis of EOCRC compared to Late-Onset Colorectal Cancer (LOCRC), and the …

IMMUNOREACT 6: weak immune surveillance characterizes early-onset rectal cancer

G Spolverato, M Fassan, M Scarpa… - British Journal of …, 2023 - academic.oup.com
Background Colon cancer in young patients is often associated with hereditary syndromes;
however, in early-onset rectal cancer, mutations of these genes are rarely observed. The …

A Novel DNA Variant in SMARCA4 Gene Found in a Patient Affected by Early Onset Colon Cancer

F Di Maggio, G Boccia, M Nunziato, M Filotico… - International Journal of …, 2024 - mdpi.com
Colorectal cancer is the third leading cause of death from neoplasia worldwide. Thanks to
new screening programs, we are now seeing an increase in Early Onset of ColoRectal …

Early-onset sporadic colorectal cancer: key question of early diagnosis and screening strategies

J Perea, D Winter - British Journal of Surgery, 2023 - academic.oup.com
It is estimated that worldwide nearly 2 million patients were diagnosed with colorectal cancer
in 2020, with nearly a million deaths from the disease in the same interval 1. The incidence …

Association between microsatellite status and characteristics and outcomes of early-onset compared to late-onset rectal cancer

SH Emile, N Horesh, Z Garoufalia, R Gefen… - International Journal of …, 2024 - Springer
Background Microsatellite instability (MSI) is an important prognosticator for colorectal
cancer (CRC). The present study aimed to assess the impact of MSI status on the …

[HTML][HTML] Multivariate Prognostic Models for Patients with Stages I and Ii Colon Carcinoma: a Strobe-Compliant Retrospective Cohort Study

LF Oñate-Ocaña, R Herrera-Goepfert… - Revista de …, 2023 - scielo.org.mx
Resumen ONATE-OCANA, Luis F. et al. Multivariate Prognostic Models for Patients with
Stages I and Ii Colon Carcinoma: a Strobe-Compliant Retrospective Cohort Study. Rev …

大蹄蝠全基因组微卫星分布特征分析

邵伟伟, 乔芬, 蔡玮, 林植华, 韦力 - 兽类学报, 2023 - mammal.cn
脊椎动物基因组含有丰富的微卫星信息. 本研究对翼手目动物中的大蹄蝠全基因组及其基因的微
卫星分布特征进行分析, 并对含有微卫星编码序列的基因进行注释分析. 结果表明 …

Chromosomal breaks: another differential gap between early-onset and late-onset colorectal cancers

J Perea, JL García, LA Corchete, M Martí… - British Journal of …, 2024 - academic.oup.com
Colorectal cancer remains the second most common cause of cancer-related death in
Western countries in terms of incidence and mortality, and is the most common tumour type …