From experimental studies to computational approaches: recent trends in designing novel therapeutics for amyloidogenesis
Amyloidosis is a condition marked by misfolded proteins that build up in tissues and
eventually destroy organs. It has been connected to a number of fatal illnesses, including …
eventually destroy organs. It has been connected to a number of fatal illnesses, including …
Differential effects of SARS-CoV-2 amyloidogenic segments on the aggregation and toxicity of human islet amyloid polypeptide within membrane environments
J Zhang, VSD Mesias, AD Chesney, VK Anand… - International Journal of …, 2024 - Elsevier
Human islet amyloid polypeptide (hIAPP), an intrinsically disordered protein (IDP), plays a
significant role in the pathogenesis of type 2 diabetes through its aggregation. Recent …
significant role in the pathogenesis of type 2 diabetes through its aggregation. Recent …
Polymeric Materials as a Promising Platform for Suppressing Protein Aggregation Process
The idea of designing novel anti-amyloid therapeutic agents has generated a lot of scientific
interest and the potential for treating a variety of human pathophysiologies, such as …
interest and the potential for treating a variety of human pathophysiologies, such as …