Safety and efficacy of phage therapy in difficult-to-treat infections: a systematic review

S Uyttebroek, B Chen, J Onsea… - The Lancet Infectious …, 2022 - thelancet.com
According to the latest reports from WHO, the incidence of antibiotic-resistant bacterial
infections is increasing worldwide, resulting in increased morbidity and mortality and a rising …

Therapeutic Strategies for Emerging Multidrug-Resistant Pseudomonas aeruginosa

AJ Kunz Coyne, A El Ghali, D Holger, N Rebold… - Infectious diseases and …, 2022 - Springer
Multidrug-resistant (MDR) and extensively drug-resistant (XDR) Pseudomonas aeruginosa
isolates are frequent causes of serious nosocomial infections that may compromise the …

Emerging strategies to combat ESKAPE pathogens in the era of antimicrobial resistance: a review

MS Mulani, EE Kamble, SN Kumkar… - Frontiers in …, 2019 - frontiersin.org
The acronym ESKAPE includes six nosocomial pathogens that exhibit multidrug resistance
and virulence: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae …

Phage therapy in the postantibiotic era

FL Gordillo Altamirano, JJ Barr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Antibiotic resistance is arguably the biggest current threat to global health. An increasing
number of infections are becoming harder or almost impossible to treat, carrying high …

[HTML][HTML] Advantages and limitations of bacteriophages for the treatment of bacterial infections

N Principi, E Silvestri, S Esposito - Frontiers in pharmacology, 2019 - frontiersin.org
Bacteriophages (BPs) are viruses that can infect and kill bacteria without any negative effect
on human or animal cells. For this reason, it is supposed that they can be used, alone or in …

[HTML][HTML] Formulation, stabilisation and encapsulation of bacteriophage for phage therapy

DJ Malik, IJ Sokolov, GK Vinner, F Mancuso… - Advances in colloid and …, 2017 - Elsevier
Against a backdrop of global antibiotic resistance and increasing awareness of the
importance of the human microbiota, there has been resurgent interest in the potential use of …

Impact of antibiotics on the human microbiome and consequences for host health

DV Patangia, C Anthony Ryan, E Dempsey… - …, 2022 - Wiley Online Library
It is well established that the gut microbiota plays an important role in host health and is
perturbed by several factors including antibiotics. Antibiotic‐induced changes in microbial …

Phages for biofilm removal

C Ferriol-González, P Domingo-Calap - Antibiotics, 2020 - mdpi.com
Biofilms are clusters of bacteria that live in association with surfaces. Their main
characteristic is that the bacteria inside the biofilms are attached to other bacterial cells and …

Recent progress in polymer research to tackle infections and antimicrobial resistance

MM Konai, B Bhattacharjee, S Ghosh… - …, 2018 - ACS Publications
Global health is increasingly being threatened by the rapid emergence of drug-resistant
microbes. The ability of these microbes to form biofilms has further exacerbated the scenario …

Phage treatment of human infections

ST Abedon, SJ Kuhl, BG Blasdel, EM Kutter - Bacteriophage, 2011 - Taylor & Francis
Phages as bactericidal agents have been employed for 90 years as a means of treating
bacterial infections in humans as well as other species, a process known as phage therapy …