Cardiac phenotype and angiotensin II levels in AT1a, AT1b, and AT2 receptor single, double, and triple knockouts

JHM Van Esch, F Gembardt… - Cardiovascular …, 2010 - academic.oup.com
Aims Our aim was to determine the contribution of the three angiotensin (Ang) II receptor
subtypes (AT1a, AT1b, AT2) to coronary responsiveness, cardiac histopathology, and tissue …

Effects of angiotensin II and its metabolites in the rat coronary vascular bed: is angiotensin III the preferred ligand of the angiotensin AT2 receptor?

JHM van Esch, CR Oosterveer, WW Batenburg… - European journal of …, 2008 - Elsevier
Aminopeptidases metabolize angiotensin II to angiotensin-(2–8)(= angiotensin III) and
angiotensin-(3–8)(= angiotensin IV), and carboxypeptidases generate angiotensin-(1–7) …

Suppressor of cytokine signaling-3 provides a novel interface in the cross-talk between angiotensin II and insulin signaling systems

VC Calegari, M Alves, PK Picardi, RY Inoue… - …, 2005 - academic.oup.com
Angiotensin II inhibits insulin-induced activation of phosphatidylinositol 3-kinase through a
mechanism, at least in part, dependent on serine phosphorylation of the insulin receptor and …

Angiotensin and calcium signaling in the pituitary and hypothalamus

C Suárez, IG Tornadú, C Cristina, J Vela… - Cellular and molecular …, 2002 - Springer
In the rat pituitary, angiotensin type 1B receptors (AT 1B) are located in lactotrophs and
corticotrophs. 2) Activation of AT 1B receptors are coupled to G q/11 (Guanine protein …

Estradiol and angiotensin II crosstalk in hydromineral balance: Role of the ERK1/2 and JNK signaling pathways

G Almeida-Pereira, R Coletti, AS Mecawi, LC Reis… - Neuroscience, 2016 - Elsevier
The angiotensin II (ANGII) receptor AT1 plays an important role in the control of
hydromineral balance, mediating the dipsogenic and natriorexigenic effects and …

AT2 receptor‐mediated vasodilation in the mouse heart depends on AT1A receptor activation

JHM van Esch, MP Schuijt, J Sayed… - British journal of …, 2006 - Wiley Online Library
1 Angiotensin (Ang) II type 2 (AT2) receptors are believed to counteract Ang II type 1 (AT1)
receptor‐mediated effects. Here, we investigated AT2 receptor‐mediated effects on coronary …

Suppressor of cytokine signaling 3 is induced by angiotensin II in heart and isolated cardiomyocytes, and participates in desensitization

VC Calegari, RMN Bezerra, MA Torsoni… - …, 2003 - academic.oup.com
Angiotensin II (Ang II) exerts a potent growth stimulus on the heart and vascular wall.
Activation of the Janus kinase/signal transducer and activator of transcription (JAK/STAT) …

Effects of acute stress on the day of proestrus on sexual behavior and ovulation in female rats: participation of the angiotensinergic system

MVF Donadio, A Kunrath, KL Corezola, CR Franci… - Physiology & …, 2007 - Elsevier
Physical or emotional stress can affect the female reproductive physiology and angiotensin II
(Ang II) is a hormone that participates in the stress response and also in the control of …

Effects of renovascular hypertension on reproductive function in male rats

MK Breigeiron, AB Lucion, GL Sanvitto - Life sciences, 2007 - Elsevier
OBJECTIVE: The present study investigated the effects of renovascular hypertension (2K/1C
model) on the reproductive function of male rats, represented by sexual behavior, plasma …

17β-Estradiol attenuates p38MAPK activity but not PKCα induced by angiotensin II in the brain

G Almeida-Pereira, T Vilhena-Franco… - Journal of …, 2019 - joe.bioscientifica.com
17β-Estradiol (E2) has been shown to modulate the renin–angiotensin system in
hydromineral and blood pressure homeostasis mainly by attenuating angiotensin II (ANGII) …