Point-of-care diagnostics: recent developments in a connected age

S Nayak, NR Blumenfeld, T Laksanasopin… - Analytical …, 2017 - ACS Publications
The field of point-of-care (POC) diagnostics offers the tantalizing possibility of providing
rapid diagnostic results in nonlaboratory settings. Here, we review progress in this research …

Diagnosis of Ebola virus disease: past, present, and future

MJ Broadhurst, TJG Brooks… - Clinical microbiology …, 2016 - Am Soc Microbiol
Laboratory diagnosis of Ebola virus disease plays a critical role in outbreak response efforts;
however, establishing safe and expeditious testing strategies for this high-biosafety-level …

Update on tuberculosis biomarkers: from correlates of risk, to correlates of active disease and of cure from disease

D Goletti, MR Lee, JY Wang, N Walter… - …, 2018 - Wiley Online Library
Tuberculosis (TB) remains a devastating disease, yet despite its enormous toll on global
health, tools to control TB are insufficient and often outdated. TB Biomarkers (TB‐BM) would …

Ebola virus persistence in semen of male survivors

TM Uyeki, BR Erickson, S Brown… - Clinical Infectious …, 2016 - academic.oup.com
We investigated the duration of Ebola virus (EBOV) RNA and infectious EBOV in semen
specimens of 5 Ebola virus disease (EVD) survivors. EBOV RNA and infectious EBOV was …

Diagnostics of Ebola virus

A Bettini, D Lapa, AR Garbuglia - Frontiers in Public Health, 2023 - frontiersin.org
Ebola is a highly pathogenic virus, which in humans reaches a mortality rate above 50%.
Due to a lack of laboratories in territories where Ebola viruses are endemic and the limited …

Diagnostics for Nipah virus: a zoonotic pathogen endemic to Southeast Asia

LT Mazzola, C Kelly-Cirino - BMJ global health, 2019 - gh.bmj.com
Nipah virus (NiV) is an emerging pathogen that, unlike other priority pathogens identified by
WHO, is endemic to Southeast Asia. It is most commonly transmitted through exposure to …

Find the right sample: A study on the versatility of saliva and urine samples for the diagnosis of emerging viruses

M Niedrig, P Patel, AA El Wahed, R Schädler… - BMC infectious …, 2018 - Springer
Background The emergence of different viral infections during the last decades like dengue,
West Nile, SARS, chikungunya, MERS-CoV, Ebola, Zika and Yellow Fever raised some …

Performance of the GeneXpert Ebola assay for diagnosis of Ebola virus disease in Sierra Leone: a field evaluation study

AE Semper, MJ Broadhurst, J Richards… - PLoS …, 2016 - journals.plos.org
Background Throughout the Ebola virus disease (EVD) epidemic in West Africa, field
laboratory testing for EVD has relied on complex, multi-step real-time reverse transcription …

Viral hemorrhagic fever diagnostics

LD Racsa, CS Kraft, GG Olinger… - Clinical Infectious …, 2016 - academic.oup.com
There are 4 families of viruses that cause viral hemorrhagic fever (VHF), including
Filoviridae. Ebola virus is one virus within the family Filoviridae and the cause of the current …

Comparative evaluation of the diagnostic performance of the prototype Cepheid GeneXpert Ebola assay

P Jansen van Vuren, A Grobbelaar… - Journal of clinical …, 2016 - Am Soc Microbiol
The Ebola virus disease (EVD) outbreak in West Africa has highlighted an urgent need for
point-of-care (POC) assays for the diagnosis of this devastating disease in resource-limited …