Metabolomics and type 2 diabetes risk: an updated systematic review and meta-analysis of prospective cohort studies
BACKGROUND Due to the rapidly increasing availability of metabolomics data in
prospective studies, an update of the meta evidence on metabolomics and type 2 diabetes …
prospective studies, an update of the meta evidence on metabolomics and type 2 diabetes …
Trimethylamine N-oxide in relation to cardiometabolic health—cause or effect?
C Papandreou, M Moré, A Bellamine - Nutrients, 2020 - mdpi.com
Trimethylamine-N-oxide (TMAO) is generated in a microbial-mammalian co-metabolic
pathway mainly from the digestion of meat-containing food and dietary quaternary amines …
pathway mainly from the digestion of meat-containing food and dietary quaternary amines …
[HTML][HTML] Gut microbiota–derived metabolite trimethylamine-N-oxide and multiple health outcomes: an umbrella review and updated meta-analysis
ABSTRACT Background Trimethylamine-N-oxide (TMAO) is a gut microbiota–derived
metabolite produced from dietary nutrients. Many studies have discovered that circulating …
metabolite produced from dietary nutrients. Many studies have discovered that circulating …
[HTML][HTML] Gut microbiota and ischemic stroke: the role of trimethylamine N-oxide
HS Nam - Journal of Stroke, 2019 - ncbi.nlm.nih.gov
Trimethylamine N-oxide (TMAO) is produced when trimethylamine, a waste product of gut
microbes, is converted via hepatic flavin monooxygenases. As TMAO is a potential causative …
microbes, is converted via hepatic flavin monooxygenases. As TMAO is a potential causative …
Association of trimethylamine N-oxide and related metabolites in plasma and incident type 2 diabetes: the cardiovascular health study
Importance Although rodent studies suggest that trimethylamineN-oxide (TMAO) influences
glucose homeostasis and risk of type 2 diabetes, evidence in humans is limited. Objective …
glucose homeostasis and risk of type 2 diabetes, evidence in humans is limited. Objective …
Amino acids, microbiota-related metabolites, and the risk of incident diabetes among normoglycemic Chinese adults: Findings from the 4C study
S Wang, M Li, H Lin, G Wang, Y Xu, X Zhao, C Hu… - Cell Reports …, 2022 - cell.com
Although previous studies suggest that amino acids (AAs) and microbiota-related
metabolites (MRMs) are associated with type 2 diabetes mellitus (T2DM), the results remain …
metabolites (MRMs) are associated with type 2 diabetes mellitus (T2DM), the results remain …
Effects of Mediterranean Diet on plasma metabolites and their relationship with insulin resistance and gut microbiota composition in a crossover randomized clinical …
S Galié, J García-Gavilán, C Papandreou… - Clinical Nutrition, 2021 - Elsevier
Summary Background & aims The Mediterranean Diet (MedDiet) may decrease the
cardiometabolic risk through modulation of metabolic pathways. Furthermore, the interplay …
cardiometabolic risk through modulation of metabolic pathways. Furthermore, the interplay …
Trimethylamine N-oxide and risk of cardiovascular disease and mortality
Abstract Purpose of Review Trimethylamine N-oxide (TMAO) is a gut microbiota-dependent
metabolite produced from choline and phosphatidylcholine. Trimethylamine N-oxide was …
metabolite produced from choline and phosphatidylcholine. Trimethylamine N-oxide was …
Gut microbiota-derived metabolite trimethylamine N-oxide as a biomarker in early Parkinson's disease
Objectives This study aimed to investigate the potential of using changes in the plasma
levels of trimethylamine N-oxide (TMAO), a gut microbiota-derived metabolite, as a …
levels of trimethylamine N-oxide (TMAO), a gut microbiota-derived metabolite, as a …
Circulating trimethylamine‐N‐oxide is associated with all‐cause mortality in subjects with nonalcoholic fatty liver disease
JL Flores‐Guerrero, A Post, PR van Dijk… - Liver …, 2021 - Wiley Online Library
Abstract Background and Aims Trimethylamine‐N‐oxide (TMAO), a gut microbiota‐liver
metabolite, has been associated with cardiometabolic disease. However, whether TMAO is …
metabolite, has been associated with cardiometabolic disease. However, whether TMAO is …