1.1. Discovery of the Phospholipase A2 Superfamily Phospholipases represent one of the
earliest enzyme activities to be identified and studied, and the phospholipase A2 (PLA2) …

Recombinant techniques are routinely used for the preparation of protein samples for
structural studies including X-ray crystallography. Among other benefits, these methods …

The substitution and de-substitution of carbohydrate materials are important steps in the
biosynthesis and/or breakdown of a wide variety of biologically important polymers. The …

Mutations in the LIS1 gene cause lissencephaly, a human neuronal migration disorder. LIS1
binds dynein and the dynein-associated proteins Nde1 (formerly known as NudE), Ndel1 …

The esterases and lipases from the α/β hydrolase superfamily exhibit an enormous
sequence diversity, fold plasticity, and activities. Here, we present the comprehensive …

YesT, a putative protein from Bacillus subtilis ATCC 6633 that has been provisionally
classified as a rhamnogalacturonan acetyl esterase (RGAE) in CE‐12 family, was cloned …

Alginates are industrially important, linear copolymers of β-d-mannuronic acid (M) and its C-
5-epimer α-l-guluronic acid (G). The G residues originate from a postpolymerization reaction …

Pulmonary hemorrhage has been recognized as a major, often lethal, manifestation of
severe leptospirosis albeit the pathogenesis remains unclear. The Leptospira interrogans …

Bioinformatics analysis was focused on unique acetylesterases annotated in the CAZy
database within the CE16 family and simultaneously belonging to the SGNH hydrolase …

Insecticide and nerve agent organophosphorus (OP) compounds are potent inhibitors of the
serine hydrolase superfamily of enzymes. Nerve agents, such as sarin, soman, tabun, and …