Lysophosphatidic acid (LPA, 1-or 2-acyl-sn-glycerol 3-phosphate) is a simple phospholipid
but displays an intriguing cell biology that is mediated via interactions with G protein …

Lysophosphatidic acid (LPA) is one of the simplest glycerophospholipids with one fatty acid
chain and a phosphate group as a polar head. Although LPA had been viewed just as a …

Lysophosphatidylcholine (LPC) and lysophosphatidic acid (LPA), the most prominent
lysoglycerophospholipids, are emerging as a novel class of inflammatory lipids, joining …

The lysophospholipids, sphingosine-1-phosphate (S1P), lysophosphatidic acid (LPA),
sphingosylphosphorylcholine (SPC) and lysophosphatidylcholine (LPC), activate diverse …

Lysophosphatidic acid is one of the most attractive phospholipid mediator with multiple
biological functions and is implicated in various human diseases. In the past ten years much …

Lipid phosphates initiate key signaling cascades in cell activation. Lysophosphatidate (LPA)
and sphingosine 1‐phosphate (S1P) are produced by activated platelets. LPA is also formed …

The many biological responses documented for lysophospholipids that include
lysophosphatidic acid and sphingosine 1-phosphate can be mechanistically attributed to …

Lipid phosphate phosphatases (LPPs) regulate cell signaling by modifying the
concentrations of lipid phosphates versus their dephosphorylated products. The ecto-activity …

Lipid phosphate phosphatases (LPPs) are a group of enzymes that belong to a
phosphatase/phosphotransferase family. Mammalian LPPs consist of three isoforms: LPP1 …

Lysophosphatidic acid (LPA) is both a potential marker and a therapeutic target for ovarian
cancer. It is critical to identify the sources of elevated LPA levels in ascites and blood of …