Cathepsin L targeting in cancer treatment

DR Sudhan, DW Siemann - Pharmacology & therapeutics, 2015 - Elsevier
Proteolytic enzymes may serve as promising targets for novel therapeutic treatment
strategies seeking to impede cancer progression and metastasis. One such enzyme is …

Cancer-associated bone disease

R Rizzoli, JJ Body, ML Brandi, J Cannata-Andia… - Osteoporosis …, 2013 - Springer
Bone is commonly affected in cancer. Cancer-induced bone disease results from the primary
disease, or from therapies against the primary condition, causing bone fragility. Bone …

American Cancer Society prostate cancer survivorship care guidelines

TA Skolarus, AMD Wolf, NL Erb… - CA: a cancer journal …, 2014 - Wiley Online Library
Answer questions and earn CME/CNE Prostate cancer survivors approach 2.8 million in
number and represent 1 in 5 of all cancer survivors in the United States. While guidelines …

Breast cancer treatment and its effects on aging

L Chang, LS Weiner, SJ Hartman, S Horvath… - Journal of geriatric …, 2019 - Elsevier
Breast cancer is the most common cancer of women in the United States. It is also proving to
be one of the most treatable. Early detection, surgical intervention, therapeutic radiation …

Combinations of calcitriol with anticancer treatments for breast cancer: an update

M Segovia-Mendoza, J García-Quiroz, L Díaz… - International journal of …, 2021 - mdpi.com
Preclinical, clinical, and epidemiological studies indicate that vitamin D3 (VD) deficiency is a
risk factor for the development of breast cancer. Underlying mechanisms include the ability …

[HTML][HTML] Skeletal response to resistance and impact training in prostate cancer survivors

KM Winters-Stone, JC Dobek, JA Bennett… - Medicine and science …, 2014 - ncbi.nlm.nih.gov
Methods We randomized 51 PCS (mean age: 70.2 yrs) currently prescribed ADT to
participate in one year of impact+ resistance training (Prevent Osteoporosis with Impact+ …

Extracellular vesicles from human umbilical cord blood ameliorate bone loss in senile osteoporotic mice

Y Hu, R Xu, CY Chen, SS Rao, K Xia, J Huang, H Yin… - Metabolism, 2019 - Elsevier
Objective Senile osteoporosis is one of the most common age-related diseases worldwide.
Accumulating evidences have indicated that young blood can reverse age-related …

Calcium and vitamin D supplementation during androgen deprivation therapy for prostate cancer: a critical review

M Datta, GG Schwartz - The oncologist, 2012 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to:
Describe the prevalence of bone loss with androgen deprivation therapy for prostate cancer …

Long term toxicity of cancer treatment in older patients

A Shahrokni, A Wu, J Carter… - Clinics in geriatric …, 2015 - pmc.ncbi.nlm.nih.gov
With earlier cancer diagnosis among older cancer patients, the possibility of curing cancer
increases. However, cancer treatment may have long lasting impact on older cancer …

Management of osteoporosis among the elderly with other chronic medical conditions

JR Curtis, MM Safford - Drugs & aging, 2012 - Springer
Osteoporosis is a highly prevalent chronic disease in the US and worldwide. The most
serious consequence of this disorder is fractures, which have a serious negative impact on …