From the moment of creation to the moment of death, the heart works tirelessly to circulate
blood, being a critical organ to sustain life. As a non-stopping pumping machine, it operates …

Left ventricular assist device (LVAD) therapy has become an established treatment option
for patients with advanced heart failure. Broader application of this therapy has been limited …

A biomimetic analysis is presented in which an expression for the optimum vessel diameter
for the design of minimum mass branching or vascular networks in engineering applications …

Axial flow blood pumps for cardiac assistance have proven their clinical viability and benefit
in recent years. However, the clinical systems to date have no direct mechanism to decrease …

Left ventricular assist devices (LVADs) are emerging innovations that provide a feasible
alternative treatment for heart failure (HF) patients to enhance their quality of life. In this …

There is significant interest in the development and application of variable speed impeller-
pump type ventricular assist devices designed to generate pulsatile blood flow. However, no …

An automatic detection system for ventricular collapse was developed and tested in a first
clinical trial as part of a physiological speed control concept for axial flow pumps. From this …

Objective: Continuous Flow Left Ventricular Assist Devices (CFLVAD) are circulatory support
devices that are implanted in patients with end-stage heart failure. We developed a novel …

Objectives: To summarise the primary efficacy and safety results from the first international
clinical trial with the VentrAssist™ left ventricular assist device and to provide an update on …

This article describes a technique offering indirect measurements of pump pressure
differential and flow with certain accuracy independent of changes in blood viscosity. This …