Muscle fatigue is an exercise-induced reduction in maximal voluntary muscle force. It may
arise not only because of peripheral changes at the level of the muscle, but also because …

Locomotion results from intricate dynamic interactions between a central program and
feedback mechanisms. The central program relies fundamentally on a genetically …

Movement is accomplished by the controlled activation of motor unit populations. Our
understanding of motor unit physiology has been derived from experimental work on the …

Movement, the fundamental component of behavior and the principal extrinsic action of the
brain, is produced when skeletal muscles contract and relax in response to patterns of action …

Spasticity is a term, which was introduced to describe the velocity‐sensitive increased
resistance of a limb to manipulation in subjects with lesions of descending motor pathways …

All movements are generated by the activation of motoneurons, and hence their input-output
properties define the final step in processing of all motor commands. A major challenge to …

The dendrites of motoneurons are not, as once thought, passive conduits for synaptic inputs.
Instead they have voltage‐dependent channels that provide the capacity to generate a very …

Ageing is a natural process causing alterations in the neuromuscular system, which
contributes to reduced quality of life. Motor unit (MU) contributes to weakness, but the …

The excitability of spinal motoneurons is both fundamental for motor behavior and essential
in diagnosis of neural disorders. There are two mechanisms for altering this excitability. The …

Persistent inward currents (PICs) are present in many types of neurons and likely have
diverse functions. In spinal motoneurons, PICs are especially strong, primarily located in …