Secondary immunodeficiencies: an overview

KS Tuano, N Seth, J Chinen - Annals of Allergy, Asthma & Immunology, 2021 - Elsevier
Objective To review the different causes of secondary immunodeficiencies and provide
clinicians with an updated overview of potential factors that contribute to immunodeficiency …

Defining immunological dysfunction in sepsis: A requisite tool for precision medicine

JF Bermejo-Martin, D Andaluz-Ojeda, R Almansa… - Journal of Infection, 2016 - Elsevier
Objectives Immunological dysregulation is now recognised as a major pathogenic event in
sepsis. Stimulation of immune response and immuno-modulation are emerging approaches …

Surviving sepsis campaign research priorities 2023

D De Backer, CS Deutschman, J Hellman… - Critical Care …, 2024 - journals.lww.com
OBJECTIVES: To identify research priorities in the management, epidemiology, outcome,
and pathophysiology of sepsis and septic shock. DESIGN: Shortly after publication of the …

Endogenous IgG hypogammaglobulinaemia in critically ill adults with sepsis: systematic review and meta-analysis

M Shankar-Hari, N Culshaw, B Post, E Tamayo… - Intensive care …, 2015 - Springer
Purpose Plasma immunoglobulin concentrations are acutely altered in critically ill patients
with sepsis. However, the association between immunoglobulin levels on the day of sepsis …

[HTML][HTML] Correlation analysis of omega-3 fatty acids and mortality of sepsis and sepsis-induced ARDS in adults: data from previous randomized controlled trials

HS Chen, S Wang, Y Zhao, YT Luo, HS Tong, L Su - Nutrition journal, 2018 - Springer
Objective This study aimed to investigate the possible effect of omega-3 fatty acids on
reducing the mortality of sepsis and sepsis-induced acute respiratory distress syndrome …

[HTML][HTML] The protective association of endogenous immunoglobulins against sepsis mortality is restricted to patients with moderate organ failure

I Martin-Loeches, A Muriel-Bombín, R Ferrer… - Annals of intensive …, 2017 - Springer
Background Pre-evaluation of endogenous immunoglobulin levels is a potential strategy to
improve the results of intravenous immunoglobulins in sepsis, but more work has to be done …

[HTML][HTML] Prognostic value of CD4+ CD25+ Tregs as a valuable biomarker for patients with sepsis in ICU

K Chen, Q Zhou, H Shan, W Li, Z Lin - World journal of emergency …, 2015 - ncbi.nlm.nih.gov
BACKGROUND: Sepsis is a common complication of infections, burns, traumas, surgeries,
poisonings, and post-cardiopulmonary resuscitation. The present study aimed to investigate …

Dynamic monitoring of circulating CD8+ T and NK cell function in patients with septic shock

R Chen, S Qin, H Zhu, G Chang, M Li, H Lu, M Shen… - Immunology …, 2022 - Elsevier
Background: Septic shock is a great threat to human life. Our aim is to explore the immune
status and dynamic changes of circulating cytotoxic cells in septic shock patients. Methods …

[HTML][HTML] Monocyte dysfunction in decompensated cirrhosis is mediated by the prostaglandin E2-EP4 pathway

AA Maini, N Becares, L China, TH Tittanegro, A Patel… - JHEP Reports, 2021 - Elsevier
Background & Aims Infection is a major problem in advanced liver disease secondary to
monocyte dysfunction. Elevated prostaglandin (PG) E 2 is a mediator of monocyte …

Early levels in blood of immunoglobulin M and natural killer cells predict outcome in nonseptic critically ill patients

D Andaluz-Ojeda, V Iglesias, F Bobillo, M Nocito… - Journal of Critical …, 2013 - Elsevier
Purpose Critical illness results in derangements of all components of the immune response.
Nonetheless, most of the efforts evaluating immune status in critically ill patients have been …