Role of YAP1 signaling in biliary development, repair, and disease
L Molina, K Nejak-Bowen… - Seminars in liver …, 2022 - thieme-connect.com
Yes-associated protein 1 (YAP1) is a transcriptional coactivator that activates transcriptional
enhanced associate domain transcription factors upon inactivation of the Hippo signaling …
enhanced associate domain transcription factors upon inactivation of the Hippo signaling …
Single-cell transcriptomics reveals early emergence of liver parenchymal and non-parenchymal cell lineages
The cellular complexity and scale of the early liver have constrained analyses examining its
emergence during organogenesis. To circumvent these issues, we analyzed 45,334 single …
emergence during organogenesis. To circumvent these issues, we analyzed 45,334 single …
Hepatobiliary Differentiation: Principles from Embryonic Liver Development
SH Freeburg, W Goessling - Seminars in Liver Disease, 2020 - thieme-connect.com
Hepatocytes and biliary epithelial cells (BECs), the two endodermal cell types of the liver,
originate from progenitor cells called hepatoblasts. Based principally on in vitro data …
originate from progenitor cells called hepatoblasts. Based principally on in vitro data …
[PDF][PDF] Delineating migratory events in liver and heart development using single-cell transcriptomics
J Lotto - 2022 - open.library.ubc.ca
The cellular complexity and small scale of the mouse embryonic liver and heart valves have
constrained analyses probing cell type diversity and differentiation during their development …
constrained analyses probing cell type diversity and differentiation during their development …
YAP1 Signaling in Hepatobiliary Development and Oncogenesis
LM Molina - 2021 - search.proquest.com
Abstract Yes-associated protein 1 (YAP1) is critical for liver development, regeneration, and
oncogenesis. In this thesis, I studied the physiological role of YAP1 in early liver …
oncogenesis. In this thesis, I studied the physiological role of YAP1 in early liver …