Population imaging of neural activity in awake behaving mice
A longstanding goal in neuroscience has been to image membrane voltage across a
population of individual neurons in an awake, behaving mammal. Here we describe a …
population of individual neurons in an awake, behaving mammal. Here we describe a …
[HTML][HTML] Theta and gamma rhythmic coding through two spike output modes in the hippocampus during spatial navigation
Hippocampal CA1 neurons generate single spikes and stereotyped bursts of spikes.
However, it is unclear how individual neurons dynamically switch between these output …
However, it is unclear how individual neurons dynamically switch between these output …
Rapid changes in synaptic strength after mild traumatic brain injury
Traumatic brain injury (TBI) affects millions of Americans annually, but effective treatments
remain inadequate due to our poor understanding of how injury impacts neural function …
remain inadequate due to our poor understanding of how injury impacts neural function …
Distinct neuronal populations contribute to trace conditioning and extinction learning in the hippocampal CA1
Trace conditioning and extinction learning depend on the hippocampus, but it remains
unclear how neural activity in the hippocampus is modulated during these two different …
unclear how neural activity in the hippocampus is modulated during these two different …
[HTML][HTML] An interdisciplinary computational model for predicting traumatic brain injury: Linking biomechanics and functional neural networks
The brain is a complex network consisting of neuron cell bodies in the gray matter and their
axonal projections, forming the white matter tracts. These neurons are supported by an …
axonal projections, forming the white matter tracts. These neurons are supported by an …
High-Frequency Head Impact Disrupts Hippocampal Neural Ensemble Dynamics
DP Chapman, SS Sloley, AP Caccavano… - Frontiers in Cellular …, 2022 - frontiersin.org
We have recently shown that the cognitive impairments in a mouse model of high-frequency
head impact (HFHI) are caused by chronic changes to synaptic physiology. To better …
head impact (HFHI) are caused by chronic changes to synaptic physiology. To better …
Impaired glutamate receptor function underlies early activity loss of ipsilesional motor cortex after closed-head mild traumatic brain injury
T Nguyen, MH Al-Juboori, J Walerstein… - Journal of …, 2021 - liebertpub.com
Although mild traumatic brain injury (mTBI) accounts for the majority of TBI patients, the
effects and cellular and molecular mechanisms of mTBI on cortical neural circuits are still not …
effects and cellular and molecular mechanisms of mTBI on cortical neural circuits are still not …
Optogenetic interrogation of circuits following neurotrauma
S Ceto, G Courtine - Frontiers in Molecular Neuroscience, 2021 - frontiersin.org
Biological and engineering strategies for neural repair and recovery from neurotrauma
continue to emerge at a rapid pace. Until recently, studies of the impact of neurotrauma and …
continue to emerge at a rapid pace. Until recently, studies of the impact of neurotrauma and …
A Teensy microcontroller-based interface for optical imaging camera control during behavioral experiments
Background Systems neuroscience experiments often require the integration of precisely
timed data acquisition and behavioral monitoring. While specialized commercial systems …
timed data acquisition and behavioral monitoring. While specialized commercial systems …
Single Neuron Modeling Identifies Potassium Channel Modulation as Potential Target for Repetitive Head Impacts
Traumatic brain injury (TBI) and repetitive head impacts can result in a wide range of
neurological symptoms. Despite being the most common neurological disorder in the world …
neurological symptoms. Despite being the most common neurological disorder in the world …