Antimicrobial resistance (AMR) is a challenge to human wellbeing the world over and is one
of the more serious public health concerns. AMR has the potential to emerge as a serious …

Infections arising from multidrug-resistant pathogenic bacteria are spreading rapidly
throughout the world and threaten to become untreatable. The origins of resistance are …

Although metabolism plays an active role in antibiotic lethality, antibiotic resistance is
generally associated with drug target modification, enzymatic inactivation, and/or transport …

We have come a long way in the last years of developing analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …

Acinetobacter baumannii is a nosocomial pathogen and gram-negative coccobacillus that is
responsible for opportunistic infections, pneumonia, and infections of the urinary tract …

Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …

Bacterial mechanisms of drug resistance operate at sequential lines of defense tackling drug
at entry, accumulation, target binding, or downstream toxicity. These mechanisms are …

Herbicides are one of the most widely used chemicals in agriculture. While they are known
to be harmful to nontarget organisms, the effects of herbicides on the composition and …

Antibiotic resistance is currently one of the most important public health problems. The
golden age of antibiotic discovery ended decades ago, and new approaches are urgently …

Increasing antibiotic resistance urges for new technologies for studying microbes and
antimicrobial mechanism of action. We adapted thermal proteome profiling (TPP) to probe …