Phytocannabinoids in the pharmacotherapy of psoriasis

A Wroński, I Jarocka-Karpowicz, A Stasiewicz… - Molecules, 2023 - mdpi.com
Phytocannabinoids are naturally occurring compounds, the main source of which is
Cannabis sativa L. Through direct action or interaction with G protein-coupled receptors …

Changes in proteome of fibroblasts isolated from psoriatic skin lesions

A Gęgotek, P Domingues, A Wroński… - International journal of …, 2020 - mdpi.com
The dermal fibroblasts are in constant contact with the cells of the immune system and skin
epidermis. Therefore, they are essential for the development of lesions in psoriasis. The aim …

ZnO NPs delay the recovery of psoriasis-like skin lesions through promoting nuclear translocation of p-NFκB p65 and cysteine deficiency in keratinocytes

X Lai, M Wang, Y Zhu, X Feng, H Liang, J Wu… - Journal of hazardous …, 2021 - Elsevier
Background This study aimed to evaluate the safety of applying zinc oxide nanoparticles
(ZnO NPs) to pathological skin. The majority of previous studies confirmed the safety of …

A psoriasis és az oxidatív stressz

I Péter, A Jagicza, Z Ajtay, I Kiss, B Németh - Orvosi hetilap, 2016 - akjournals.com
Absztrakt A psoriasis hazánkban és világviszonylatban is a leggyakrabban előforduló
bőrbetegségek egyike. Jelentőségét hangsúlyozza a gyakran élethossziglan fennálló …

Aromatic-turmerone ameliorates imiquimod-induced psoriasis-like inflammation of BALB/c mice

YL Li, ZY Du, PH Li, L Yan, W Zhou, YD Tang… - International …, 2018 - Elsevier
Psoriasis is a usual immune-mediated inflammatory skin disease with undefined
pathogenesis. Aromatic-turmerone (ATM) is a mainly constituent of essential oil from …

The antimicrobial peptide cathelicidin exerts immunomodulatory effects via scavenger receptors

R Amagai, T Takahashi, H Terui, T Fujimura… - International Journal of …, 2023 - mdpi.com
An active form of cathelicidin antimicrobial peptide, LL-37, has immunomodulatory and
stimulatory effects, though the specific pathways are not clear. The purpose of this study was …

[HTML][HTML] Investigation of omega-3 polyunsaturated fatty acid biological activity in a tissue-engineered skin model involving psoriatic cells

M Simard, G Rioux, S Morin, C Martin, SL Guérin… - Journal of Investigative …, 2021 - Elsevier
Clinical studies have shown that diets enriched with omega-3 (also know as n-3)
polyunsaturated fatty acids could relieve the symptoms of patients with psoriasis. However …

Identification of potential biomarkers and infiltrating immune cells from scalp psoriasis

S Liu, Z Zhuang, F Liu, X Yuan, Z Zhang, X Liang, X Li… - Gene, 2024 - Elsevier
Background Scalp psoriasis seriously affects the appearance and psychological status of
patients. The aim of this study was to investigate the effect and potential mechanism of RPL9 …

Defective induction of COX-2 expression by psoriatic fibroblasts promotes pro-inflammatory activation of macrophages

J Arasa, MC Terencio, RM Andrés… - Frontiers in …, 2019 - frontiersin.org
Fibroblasts play an important role as members of the innate immune system through the
secretion of COX-2-derived inflammatory mediators such as prostaglandin E2 (PGE2) …

Rhododendrin inhibits toll-like receptor-7-mediated psoriasis-like skin inflammation in mice

YJ Jeon, SK Sah, HS Yang, JH Lee, J Shin… - … & Molecular Medicine, 2017 - nature.com
Many active compounds present in Rhododendron brachycarpum have been used in
traditional Oriental medicine for the treatment of various skin diseases. However, the precise …