Silymarin, a mixture of flavonolignan and flavonoid polyphenolic compounds extractable
from milk thistle (Silybum marianum) seeds, has anti-oxidant, anti-inflammatory, anti-cancer …

Globally, prostate cancer (PCa) is regarded as a challenging health issue, and the number
of PCa patients continues to rise despite the availability of effective treatments in recent …

In recent years, a number of natural products isolated from Chinese herbs have been found
to inhibit proliferation, induce apoptosis, suppress angiogenesis, retard metastasis and …

Cancer is a major health problem around the world. Research efforts in the last few decades
have been successful in providing better and effective treatments against both early stage …

Ethnopharmacological relevance Hepatocellular carcinoma (HCC) as the major histological
subtype of primary liver cancer remains one of the most common malignancies worldwide …

Silymarin extracted from milk thistle consisting of flavonolignan silybin has shown
chemopreventive and chemosensitizing activity against various cancers. The present review …

Signal transducer and activator of transcription 3 (STAT3) is constitutively activated in many
different types of cancer and plays a pivotal role in tumor growth and metastasis …

Skin cancer is a life threatening disease and their prevalence and risk has been increasing
over the past three decades causing significant loss to human health worldwide. Mostly skin …

Silibinin is a natural plant polyphenol with high antioxidant and anticancer properties, which
causes broad-spectrum efficacy against cancer, including cell cycle arrest and apoptosis in …

Signal transducer and activator of transcription 3 (STAT3) has a prominent role in mediating
resistance to conventional chemo-/radio-therapies and modern targeted drugs. While a …