The oral microbiome: Role of key organisms and complex networks in oral health and disease

L Sedghi, V DiMassa, A Harrington… - Periodontology …, 2021 - Wiley Online Library
States of oral health and disease reflect the compositional and functional capacities of, as
well as the interspecies interactions within, the oral microbiota. The oral cavity exists as a …

The global prevalence of early childhood caries: a systematic review with meta‐analysis using the WHO diagnostic criteria

SE Uribe, N Innes, I Maldupa - International journal of …, 2021 - Wiley Online Library
Aim To estimate the global prevalence of early childhood caries using the WHO criteria.
Design Systematic review of studies published from 1960 to 2019. Data sources: PubMed …

Expert consensus on early childhood caries management

J Zou, Q Du, L Ge, J Wang, X Wang, Y Li… - International journal of …, 2022 - nature.com
Early childhood caries (ECC) is a significant chronic disease of childhood and a rising public
health burden worldwide. ECC may cause a higher risk of new caries lesions in both primary …

Improving caries risk prediction modeling: a call for action

M Fontana, A Carrasco-Labra… - Journal of dental …, 2020 - journals.sagepub.com
Dentistry has entered an era of personalized/precision care in which targeting care to
groups, individuals, or even tooth surfaces based on their caries risk has become a reality to …

A new model for caries risk prediction in teenagers using a machine learning algorithm based on environmental and genetic factors

L Pang, K Wang, Y Tao, Q Zhi, J Zhang, H Lin - Frontiers in Genetics, 2021 - frontiersin.org
Dental caries is a multifactorial disease that can be caused by interactions between genetic
and environmental risk factors. Despite the availability of caries risk assessment tools, caries …

Genetic variants in taste genes play a role in oral microbial composition and severe early childhood caries

VC de Jesus, BA Mittermuller, P Hu, RJ Schroth… - Iscience, 2022 - cell.com
Severe early childhood caries (S-ECC) is a multifactorial disease with strong evidence of
genetic inheritance. Previous studies suggest that variants in taste genes are associated …

Genetic Preference for Sweet Taste in Mothers Associates with Mother-Child Preference and Intake

P Lif Holgerson, P Hasslöf, A Esberg, S Haworth… - Nutrients, 2023 - mdpi.com
Taste perception is a well-documented driving force in food selection, with variations in, eg,
taste receptor encoding and glucose transporter genes conferring differences in taste …

Heritability of oral microbiota and immune responses to oral bacteria

A Esberg, S Haworth, R Kuja-Halkola, PKE Magnusson… - Microorganisms, 2020 - mdpi.com
Maintaining a symbiotic oral microbiota is essential for oral and dental health, and host
genetic factors may affect the composition or function of the oral microbiota through a range …

Phenotype harmonization in the GLIDE2 oral health genomics consortium

K Divaris, S Haworth, JR Shaffer… - Journal of dental …, 2022 - journals.sagepub.com
Genetic risk factors play important roles in the etiology of oral, dental, and craniofacial
diseases. Identifying the relevant risk loci and understanding their molecular biology could …

A Polygenic Score Predicts Caries Experience in Elderly Swedish Adults

N Fries, S Haworth, JR Shaffer… - Journal of Dental …, 2024 - journals.sagepub.com
Caries is a partially heritable disease, raising the possibility that a polygenic score (PS, a
summary of an individual's genetic propensity for disease) might be a useful tool for risk …