Immunodiagnosis of tuberculosis: a dynamic view of biomarker discovery

S Kunnath-Velayudhan… - Clinical microbiology …, 2011 - Am Soc Microbiol
Infection with Mycobacterium tuberculosis causes a variety of clinical conditions ranging
from life-long asymptomatic infection to overt disease with increasingly severe tissue …

Beyond memory T cells: mechanisms of protective immunity to tuberculosis infection

P Steigler, AJ Verrall, JR Kirman - Immunology and cell biology, 2019 - Wiley Online Library
Tuberculosis (TB) is a serious infectious disease caused by infection with Mycobacterium
tuberculosis, and kills more people annually than any other single infectious agent. Although …

[HTML][HTML] A first-in-human phase 1 trial to evaluate the safety and immunogenicity of the candidate tuberculosis vaccine MVA85A-IMX313, administered to BCG …

A Minhinnick, I Satti, S Harris, M Wilkie, S Sheehan… - Vaccine, 2016 - Elsevier
Introduction There is an urgent need for a new and effective tuberculosis vaccine because
BCG does not sufficiently prevent pulmonary disease. IMX313 is a novel carrier protein …

Effect of IFN-γ, IL-12 and IL-10 cytokine production and mRNA expression in tuberculosis patients with diabetes mellitus and their household contacts

P Meenakshi, S Ramya, J Lavanya, V Vijayalakshmi… - Cytokine, 2016 - Elsevier
Objective The study was carried out to understand the influence of IFN-γ, IL-12 and IL-10
cytokine production and expression in tuberculosis patients with diabetes mellitus (TBDM) …

Exploring the immunogenicity of Rv2201-519: A T-cell epitope-based antigen derived from Mycobacterium tuberculosis AsnB with implications for tuberculosis …

X Luan, X Fan, G Li, M Li, N Li, Y Yan, X Zhao… - International …, 2024 - Elsevier
Research dedicated to diagnostic reagents and vaccine development for tuberculosis (TB) is
challenging due to the paucity of immunodominant antigens that can predict disease risk …

A Comparative Approach to Strategies for Cloning, Expression, and Purification of Mycobacterium tuberculosis Mycolyl Transferase 85B and Evaluation of Immune …

H Aghababa, A Mohabati Mobarez… - Molecular …, 2014 - Springer
Protein antigens have drawn a lot of attention from investigators working on tuberculosis
vaccines. These proteins can be used to improve the immunogenicity of the new generation …

Early diagnosis of tuberculosis-associated IgA nephropathy with ESAT-6

N Zhao, JY Sun, HP Xu, FY Sun - The Tohoku Journal of …, 2017 - jstage.jst.go.jp
IgA nephropathy (IgAN) is the most common cause of primary renal diseases worldwide,
and the early secreted antigenic target of 6 (ESAT-6) which was secreted by Mycobacterium …

[HTML][HTML] Humoral immune profiling of mycobacterial antigen recognition in sarcoidosis and Löfgren's syndrome using high-content peptide microarrays

G Ferrara, D Valentini, M Rao, J Wahlström… - International Journal of …, 2017 - Elsevier
Introduction Sarcoidosis is considered an idiopathic granulomatous disease, although
similar immunological and clinical features with tuberculosis (TB) suggest mycobacterial …

Immunoscreening of the M. tuberculosis F15/LAM4/KZN secretome library against TB patients′ sera identifies unique active-and latent-TB specific biomarkers

TE Chiliza, M Pillay, K Naidoo, B Pillay - Tuberculosis, 2019 - Elsevier
Tuberculosis (TB) protein biomarkers are urgently needed for the development of point-of-
care diagnostics, new drugs and vaccines. Mycobacterium tuberculosis extracellular and …

[PDF][PDF] Enhancement and regulation effect of myrcene on antibody response in immunization with ovalbumin and Ag85B in mice

S Uyeda, T Sharmin, T Satho, K Irie… - Asian Pac J Allergy …, 2016 - apjai-journal.org
Background: MF59, which is an adjuvant belonging to C30 member of the terpene family, is
a T helper type-2 (Th2)-biased immune enhancer. Our previous studies showed that …