Background: Hemophilia A (HA) is an X-linked recessive bleeding disorder with a high rate
of genetic heterogeneity. The present study was conducted on a large cohort of Iranian HA …

The article discusses a study on the molecular diagnosis of haemophilia A in patients from
Senegal. It highlights the significance of identifying molecular variations of the F8 gene in a …

Background and Aims: Prevalence of factor VIII inhibitors in patients with hemophilia A
varies from study to study, ranging from 15% to 30%. The important risk of inhibitor …

Las mutaciones son la fuente principal de variación genética, la misma que puede influir en
las características fenotípicas (Audesirk, Audesirk, y Byers, 2013; Solari, 2011), causando …

Factor 8 Gene Mutations and Risk of Inhibitor Development in Hemophilia A Algerian Patients
Page 1 Volume 5 • Issue 1 • 1000124 J Pharmacogenomics Pharmacoproteomics ISSN …

Hemophilia A (HA) is the most severe X-linked inherited bleeding disorder caused by
hemizygous mutations in the F8 gene. Several F8 mutations are responsible of HA including …

Since the publication of the F8 gene sequence, a large number of F8 gene mutations has
been identified. These mutations are responsible for causing hemophilia A, an inherited …

Introduction: La recherche biomédicale est le moteur de développement des connaissances
dans les domaines de la biologie et des sciences médicales, dentaires et en …

Conclusions Molecular genetic testing in haemophilia A has been implemented in most
member countries of the Balkan Medical Union. However, information is lacking whether …