Cerebral small vessel disease (SVD) is common during ageing and can present as stroke,
cognitive decline, neurobehavioural symptoms, or functional impairment. SVD frequently …

The shared role of amyloid-β (Aβ) deposition in cerebral amyloid angiopathy (CAA) and
Alzheimer disease (AD) is arguably the clearest instance of crosstalk between …

Cerebral amyloid angiopathy, which is defined by cerebrovascular deposition of amyloid β,
is a common age-related small vessel pathology associated with intracerebral haemorrhage …

Abstract Objective Vascular dementia (VaD) is the second most common cause of dementia
and a major health concern worldwide. A comprehensive review on VaD is warranted for …

Perivascular spaces (PVS) are compartments surrounding cerebral blood vessels that
become visible on MRI when enlarged. Enlarged PVS (EPVS) are commonly seen in …

Cerebral small vessel disease (cSVD) is a leading cause of ischaemic and haemorrhagic
stroke and a major contributor to dementia. Covert cSVD, which is detectable with brain MRI …

Hemorrhagic stroke is the deadliest form of stroke and includes the subtypes of intracerebral
hemorrhage and subarachnoid hemorrhage. A common cause of hemorrhagic stroke in …

Age-related phenotypic changes of cerebromicrovascular endothelial cells lead to
dysregulation of cerebral blood flow and blood-brain barrier disruption, promoting the …

Cerebral microbleeds (CMBs) are defined as hypointense foci visible on T2*-weighted and
susceptible-weighted MRI sequences. CMBs are increasingly recognised with the …

Cerebral amyloid angiopathy is a common small vessel disease in the elderly involving
vascular amyloid-β deposition. Cerebral amyloid angiopathy is one of the leading causes of …