Sepsis is an unusual systemic reaction to what is sometimes an otherwise ordinary infection,
and it probably represents a pattern of response by the immune system to injury. A hyper …

Objectives The pneumonia severity index and CURB-65 are risk assessment tools widely
used in community-acquired pneumonia (CAP). However, limitations in these prognostic …

Objective: To identify and measure recently described chemical mediators, termed
specialized pro-resolving mediators that actively regulate the resolution of acute …

Background COVID-19 pneumonia and subsequent respiratory failure is causing an
immense strain on intensive care units globally. Early prediction of severe disease enables …

Advanced glycation end products (AGEs) and their receptors are strongly implicated in the
development of diabetes complications. When stimulated by AGEs, the receptors for AGEs …

Emerging evidence links the receptor for advanced glycation endproducts (RAGE) to the
pathogenesis of tissue damage in chronic metabolic and inflammatory diseases. In human …

Acute respiratory distress syndrome (ARDS) is a frequently encountered clinical syndrome
associated with unacceptably high morbidity and mortality. 1 Since its first description in …

Etiologic diagnosis of bacterial pneumonia relies on identification of causative pathogens by
cultures, which require extended incubation periods and have limited sensitivity. Next …

Abstract Background Angiopoietin-1 (Ang-1) and 2 (Ang-2), high mobility group box 1
(HMGB1), soluble receptor for advanced glycation endproducts (sRAGE), soluble triggering …

The SARS-CoV-2 (COVID-19) pandemic is a global crisis that threatens our way of life. As of
November 18, 2020, SARS-CoV-2 has claimed more than 1,342,709 lives, with a global …