Interference of metal ions on the bioluminescent signal of firefly, Renilla, and NanoLuc luciferases in high-throughput screening assays
F Canyelles i Font, K Żukowski, MA Khan… - Frontiers in …, 2024 - frontiersin.org
Bioluminescent high-throughput screening (HTS) assays, based largely on the activity of
firefly (FLuc), Renilla (RLuc), and/or NanoLuc (NLuc) luciferases, are widely utilised in …
firefly (FLuc), Renilla (RLuc), and/or NanoLuc (NLuc) luciferases, are widely utilised in …
Design of greener drugs: aligning parameters in pharmaceutical R&D and drivers for environmental impact
R Vidaurre, I Bramke, N Puhlmann, SF Owen… - Drug discovery today, 2024 - Elsevier
Active pharmaceutical ingredients (APIs) in the environment, primarily resulting from patient
excretion, are of concern because of potential risks to wildlife. This has led to more restrictive …
excretion, are of concern because of potential risks to wildlife. This has led to more restrictive …