Structure-taste relationships of some dipeptides

RH Mazur, JM Schlatter… - Journal of the American …, 1969 - ACS Publications
The discovery of a dipeptide ester, L-Asp-L-Phe-OMe, having an intense sweet taste is
reported. Investigation of structure-taste relationshipsshowed that L-aspartic acid is critical …

Reevaluating the substrate specificity of the L-type amino acid transporter (LAT1)

HC Chien, C Colas, K Finke, S Springer… - Journal of medicinal …, 2018 - ACS Publications
The L-type amino acid transporter 1 (LAT1, SLC7A5) transports essential amino acids
across the blood–brain barrier (BBB) and into cancer cells. To utilize LAT1 for drug delivery …

Design of oxytocin analogs

K Wiśniewski - Cyclic peptide design, 2019 - Springer
The neurohypophyseal hormone oxytocin (OT) and related modulators of the oxytocin
receptor (OTR) have been the subject of intensive research for nearly seven decades …

[图书][B] The Peptides Analysis, Synthesis, Biology: Modern Techniques of Conformational Structural, and Configurational Analysis

E Gross - 2012 - books.google.com
The Peptides: Analysis, Synthesis, Biology: Volume 4: Modern Techniques of
Conformational, Structural, and Configurational Analysis is an open-ended treatise that …

Chemistry and structure-activity relations of the antidiuretic hormones

R Walter, J Rudinger, IL Schwartz - The American Journal of Medicine, 1967 - Elsevier
We have reviewed contributions of synthetic peptide chemistry to several aspects of the
biology of the posterior pituitary hormones, and have also indicated how purely biological …

Basic pharmacological properties of synthetic analogues and homologues of the neurohypophysial hormones

B Berde, RA Boissonnas - Neurohypophysial hormones and similar …, 1968 - Springer
During the last decade, nearly 200 analogues and homologues of the neurohypophysial
hormones have been synthesised in various laboratories, and the biological activities of …

Peptide science: exploring the use of chemical principles and interdisciplinary collaboration for understanding life processes

VJ Hruby - Journal of medicinal chemistry, 2003 - ACS Publications
It is a great honor to be the 2002 recipient of the American Chemical Society Ralph F.
Hirschmann Award. Ralph F. Hirschmann is one of the great pioneers of peptide research1 …

The design of peptide hormone analogs

J Rudinger - Drug Design, 1971 - books.google.com
The design of peptide hormone analogs Page 340 Chapter 9 The Design of Peptide Hormone
Analogs J. Rudinger I. Introduction................. 319 A. Special Features of Peptides as Drugs …

Structure-activity relationships of neurohypophyseal peptides

VJ Hruby, CW Smith - The Peptides, 1986 - books.google.com
The neurohypophyseal hormones oxytocin (I), arginine vasopressin (II), and their related
naturally occurring analogs (Table I) have been at the forefront of developments of modern …

Threshold and receptor reserve in the action of neurohypophyseal peptides: a study of synergists and antagonists of the hydroosmotic response of the toad urinary …

P Eggena, IL Schwartz, R Walter - The Journal of General Physiology, 1970 - rupress.org
The interrelationship of several physiological receptors which influence the hydroosmotic
response of the toad urinary bladder was studied employing neurohypophyseal peptides …